Pregnancy and Delivery Care for a Patient With a HeartMate 3.

dc.contributor.author

Jones, Sara I

dc.contributor.author

Acuff, Heather

dc.contributor.author

Best, Ryan

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Gee, Yen-Yen

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Snow, Sarah C

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Agarwal, Richa

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Rosario, Karen Flores

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Gilner, Jennifer B

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Federspiel, Jerome J

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Meng, Marie-Louise

dc.date.accessioned

2025-10-24T00:36:51Z

dc.date.available

2025-10-24T00:36:51Z

dc.date.issued

2025-06

dc.description.abstract

Background

The limited available data on pregnancies among patients with left ventricular assist devices (LVADs) in situ shows elevated rates of maternal and fetal/neonatal morbidity and mortality. The first fully magnetically levitated device providing centrifugal continuous flow, HeartMate 3 (HM3, Abbott), is the only LVAD available in the United States since 2018 and has fewer adverse patient outcomes compared with previous devices.

Case summary

A 32-year-old G5P2113 woman became pregnant 19 months after destination-therapy HM3 LVAD placement. Uncomplicated antepartum care and a cesarean delivery at 34 weeks under neuraxial anesthesia was facilitated by our institution's pregnancy heart team.

Discussion

This represents the second reported HM3-supported pregnancy resulting in a live birth. Various barriers to care guided a shared anticoagulation plan, and no hemorrhagic or thrombotic complications occurred. Our intrapartum monitoring strategy facilitated a patient-centered delivery and postpartum experience while maintaining excellent patient safety.
dc.identifier

S2666-0849(25)00308-0

dc.identifier.issn

2666-0849

dc.identifier.issn

2666-0849

dc.identifier.uri

https://hdl.handle.net/10161/33441

dc.language

eng

dc.publisher

Elsevier BV

dc.relation.ispartof

JACC. Case reports

dc.relation.isversionof

10.1016/j.jaccas.2025.103536

dc.rights.uri

https://creativecommons.org/licenses/by-nc/4.0

dc.subject

anesthesia

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anticoagulation

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cardiac assist devices

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cardiomyopathy

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heart failure

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pregnancy

dc.title

Pregnancy and Delivery Care for a Patient With a HeartMate 3.

dc.type

Journal article

duke.contributor.orcid

Rosario, Karen Flores|0000-0001-6679-6345

duke.contributor.orcid

Gilner, Jennifer B|0000-0002-8996-2972

duke.contributor.orcid

Federspiel, Jerome J|0000-0003-0321-6280

duke.contributor.orcid

Meng, Marie-Louise|0000-0001-8089-3993

pubs.begin-page

103536

pubs.issue

13

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

pubs.organisational-group

Staff

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Basic Science Departments

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Clinical Science Departments

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Anesthesiology

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Anesthesiology, Women's

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Medicine

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Obstetrics and Gynecology

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Medicine, Cardiology

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Medicine, Hematology

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Obstetrics and Gynecology, Maternal Fetal Medicine

pubs.organisational-group

Population Health Sciences

pubs.publication-status

Published

pubs.volume

30

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