Revision Free Loss of Sagittal Correction > 3 Years After Adult Spinal Deformity Surgery: Who and Why?
Date
2023-10
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Abstract
Study design
Multicenter retrospective cohort study.Objective
To investigate risk factors for loss of correction within the instrumented lumbar spine following ASD surgery.Summary of background data
The sustainability of adult deformity (ASD) surgery remains a health care challenge. Malalignment is a major reason for revision surgery.Methods
321 patients who underwent fusion of the lumbar spine (≥5 levels, LIV pelvis) with a revision-free follow-up ≥3 years were identified. Patients were stratified by change in PI-LL from 6 weeks to 3 years postop as Maintained vs. Loss >5°. Those with instrumentation failure (broken rod, screw pullout, etc.) were excluded before comparisons. Demographics, surgical data, and radiographic alignment were compared. Repeated measure ANOVA was performed to evaluate the maintenance of the correction for L1-L4 and L4-S1. Multivariate logistic regression was conducted to identify independent surgical predictors of correction loss.Results
The cohort had a mean age of 64 yrs, mean BMI 28 kg/m 2 , 80% female. 82 patients (25.5%) lost >5° of PI-LL correction (mean loss 10±5°). After exclusion of patients with instrumentation failure, 52 Loss were compared to 222 Maintained. Demographics, osteotomies, 3CO, IBF, use of BMP, rod material, rod diameter, and fusion length were not significantly different. L1-S1 screw orientation angle was 1.3±4.1 from early postop to 3 years ( P =0.031), but not appreciably different at L4-S1 (-0.1±2.9 P =0.97). Lack of a supplemental rod (OR 4.0, P =0.005) and fusion length (OR 2.2, P =0.004) were associated with loss of correction.Conclusions
Approximately a quarter of revision-free patients lose an average of 10° of their 6-week correction by 3 years. Lordosis is lost proximally through the instrumentation (i.e. tulip/shank angle shifts and/or rod bending). The use of supplemental rods and avoiding sagittal overcorrection may help mitigate this loss.Type
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Lovecchio, Francis, Renaud Lafage, Han Jo Kim, Shay Bess, Christopher Ames, Munish Gupta, Peter Passias, Eric Klineberg, et al. (2023). Revision Free Loss of Sagittal Correction > 3 Years After Adult Spinal Deformity Surgery: Who and Why?. Spine. 10.1097/brs.0000000000004852 Retrieved from https://hdl.handle.net/10161/29329.
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Scholars@Duke

Peter Passias
Throughout my medical career, I have remained dedicated to improving my patients' quality of life. As a specialist in adult cervical and spinal deformity surgery, I understand the significant impact our interventions have on individuals suffering from debilitating pain and physical and mental health challenges. Spinal deformity surgery merges the complexities of spinal biomechanics with the needs of an aging population. My research focuses on spinal alignment, biomechanics, innovative surgical techniques, and health economics to ensure value-based care that enhances patient outcomes.

Christopher Ignatius Shaffrey
I have more than 25 years of experience treating patients of all ages with spinal disorders. I have had an interest in the management of spinal disorders since starting my medical education. I performed residencies in both orthopaedic surgery and neurosurgery to gain a comprehensive understanding of the entire range of spinal disorders. My goal has been to find innovative ways to manage the range of spinal conditions, straightforward to complex. I have a focus on managing patients with complex spinal disorders. My patient evaluation and management philosophy is to provide engaged, compassionate care that focuses on providing the simplest and least aggressive treatment option for a particular condition. In many cases, non-operative treatment options exist to improve a patient’s symptoms. I have been actively engaged in clinical research to find the best ways to manage spinal disorders in order to achieve better results with fewer complications.
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