Ghrelin.

dc.contributor.author

Müller, TD

dc.contributor.author

Nogueiras, R

dc.contributor.author

Andermann, ML

dc.contributor.author

Andrews, ZB

dc.contributor.author

Anker, SD

dc.contributor.author

Argente, J

dc.contributor.author

Batterham, RL

dc.contributor.author

Benoit, SC

dc.contributor.author

Bowers, CY

dc.contributor.author

Broglio, F

dc.contributor.author

Casanueva, FF

dc.contributor.author

D'Alessio, D

dc.contributor.author

Depoortere, I

dc.contributor.author

Geliebter, A

dc.contributor.author

Ghigo, E

dc.contributor.author

Cole, PA

dc.contributor.author

Cowley, M

dc.contributor.author

Cummings, DE

dc.contributor.author

Dagher, A

dc.contributor.author

Diano, S

dc.contributor.author

Dickson, SL

dc.contributor.author

Diéguez, C

dc.contributor.author

Granata, R

dc.contributor.author

Grill, HJ

dc.contributor.author

Grove, K

dc.contributor.author

Habegger, KM

dc.contributor.author

Heppner, K

dc.contributor.author

Heiman, ML

dc.contributor.author

Holsen, L

dc.contributor.author

Holst, B

dc.contributor.author

Inui, A

dc.contributor.author

Jansson, JO

dc.contributor.author

Kirchner, H

dc.contributor.author

Korbonits, M

dc.contributor.author

Laferrère, B

dc.contributor.author

LeRoux, CW

dc.contributor.author

Lopez, M

dc.contributor.author

Morin, S

dc.contributor.author

Nakazato, M

dc.contributor.author

Nass, R

dc.contributor.author

Perez-Tilve, D

dc.contributor.author

Pfluger, PT

dc.contributor.author

Schwartz, TW

dc.contributor.author

Seeley, RJ

dc.contributor.author

Sleeman, M

dc.contributor.author

Sun, Y

dc.contributor.author

Sussel, L

dc.contributor.author

Tong, J

dc.contributor.author

Thorner, MO

dc.contributor.author

van der Lely, AJ

dc.contributor.author

van der Ploeg, LHT

dc.contributor.author

Zigman, JM

dc.contributor.author

Kojima, M

dc.contributor.author

Kangawa, K

dc.contributor.author

Smith, RG

dc.contributor.author

Horvath, T

dc.contributor.author

Tschöp, MH

dc.coverage.spatial

Germany

dc.date.accessioned

2017-10-01T17:26:45Z

dc.date.available

2017-10-01T17:26:45Z

dc.date.issued

2015-06

dc.description.abstract

BACKGROUND: The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the regulation of systemic energy metabolism. SCOPE OF REVIEW: In this review, we discuss the diverse biological functions of ghrelin, the regulation of its secretion, and address questions that still remain 15 years after its discovery. MAJOR CONCLUSIONS: In recent years, ghrelin has been found to have a plethora of central and peripheral actions in distinct areas including learning and memory, gut motility and gastric acid secretion, sleep/wake rhythm, reward seeking behavior, taste sensation and glucose metabolism.

dc.identifier

https://www.ncbi.nlm.nih.gov/pubmed/26042199

dc.identifier

S2212-8778(15)00060-5

dc.identifier.issn

2212-8778

dc.identifier.uri

https://hdl.handle.net/10161/15585

dc.language

eng

dc.publisher

Elsevier GmbH

dc.relation.ispartof

Mol Metab

dc.relation.isversionof

10.1016/j.molmet.2015.03.005

dc.subject

Ghrelin

dc.subject

Growth hormone segretagogue receptor

dc.title

Ghrelin.

dc.type

Journal article

duke.contributor.orcid

D'Alessio, D|0000-0003-4155-4870

pubs.author-url

https://www.ncbi.nlm.nih.gov/pubmed/26042199

pubs.begin-page

437

pubs.end-page

460

pubs.issue

6

pubs.organisational-group

Clinical Science Departments

pubs.organisational-group

Duke

pubs.organisational-group

Duke Molecular Physiology Institute

pubs.organisational-group

Institutes and Centers

pubs.organisational-group

Medicine

pubs.organisational-group

Medicine, Endocrinology, Metabolism, and Nutrition

pubs.organisational-group

School of Medicine

pubs.publication-status

Published online

pubs.volume

4

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