Synthesis, characterization, DNA binding, topoisomerase inhibition, and apoptosis induction studies of a novel cobalt(III) complex with a thiosemicarbazone ligand

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10.1016/j.jinorgbio.2019.110907

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Beebe, Stephen J, Michael J Celestine, Jimmie L Bullock, Shayna Sandhaus, Jessa Faye Arca, Donald M Cropek, Tekettay A Ludvig, Sydney R Foster, et al. (2020). Synthesis, characterization, DNA binding, topoisomerase inhibition, and apoptosis induction studies of a novel cobalt(III) complex with a thiosemicarbazone ligand. Journal of Inorganic Biochemistry, 203. pp. 110907–110907. 10.1016/j.jinorgbio.2019.110907 Retrieved from https://hdl.handle.net/10161/21380.

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Beckford

Floyd A Beckford

Professor of Chemistry at Duke Kunshan University

Floyd Beckford has a B.Sc. (Hons) in chemistry and a Ph.D. in inorganic chemistry from the University of the West Indies, Jamaica. He was a postdoctoral fellow at Texas A&M University. Before joining Duke Kunshan, he was the Van Daniel Endowed Chair in Chemistry at the University of Virginia’s College, Wise, and previously held faculty positions at Lyon College, Arkansas, and the University of Toledo, Ohio. He was a Fulbright-University of Turku (Finland) Scholar in 2018.

His research focus is the field of medicinal inorganic chemistry. Specifically, he is interested in the potential of transition metal compounds, particularly those of ruthenium, manganese, zinc and copper, to be used as proto-pharmaceuticals. Their use as agents in anticancer, antibacterial, and anti-diabetic chemotherapy is of primary interest. This is a multidisciplinary process involving chemistry, biology and biochemistry. He is also interested in environmental chemistry from the standpoint of Contaminants of Emerging Concern. His teaching interests at Duke Kunshan include inorganic, organic and general chemistry.


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