Histoplasmosis among hospitalized febrile patients in northern Tanzania.

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2012-08

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Abstract

Histoplasmosis may be common in East Africa but the diagnosis is rarely confirmed. We report 9 (0.9%) cases of probable histoplasmosis retrospectively identified among 970 febrile inpatients studied in northern Tanzania. Median (range) age was 31 (6, 44) years, 6 (67%) were female, 6 (67%) HIV-infected; 7 (78%) were clinically diagnosed with tuberculosis or bacterial pneumonia. Histoplasmosis is an important cause of febrile illness in Tanzania but is rarely considered in the differential diagnosis. Increased clinician awareness and availability of reliable diagnostic tests may improve patient outcomes.

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Adolescent, Adult, Child, Diagnosis, Differential, Female, Fever, HIV Seropositivity, Histoplasma, Histoplasmosis, Hospitalization, Humans, Male, Retrospective Studies, Tanzania, Tuberculosis, Young Adult

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https://hdl.handle.net/10161/13783

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10.1016/j.trstmh.2012.05.009

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Lofgren, Sarah M, Emily J Kirsch, Venance P Maro, Anne B Morrissey, Levina J Msuya, Grace D Kinabo, Wilbrod Saganda, Helmut C Diefenthal, et al. (2012). Histoplasmosis among hospitalized febrile patients in northern Tanzania. Trans R Soc Trop Med Hyg, 106(8). pp. 504–507. 10.1016/j.trstmh.2012.05.009 Retrieved from https://hdl.handle.net/10161/13783.

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Crump

John Andrew Crump

Adjunct Professor in the Department of Medicine

I am an Adjunct Professor of Medicine, Pathology, and Global Health. My work with Duke University is primarily based in northern Tanzania where I am former Site Leader and current Principal Investigator on projects linked to Duke University’s collaborative research program at Kilimanjaro Christian Medical Centre. I oversee the design and implementation of research studies on infectious diseases, particularly febrile illness, invasive bacterial disease, zoonotic infections, and infectious diseases diagnostics. In addition, I am Professor of Medicine, Pathology, and Global Health at the University of Otago and a medical epidemiologist with the US Centers for Disease Control and Prevention (CDC). My CDC work focuses on non-malaria febrile illness.

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