Heated Intravesical Chemotherapy: Biology and Clinical Utility.

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2020-02

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Abstract

Non-muscle-invasive bladder cancer can be a challenging disease to manage. In recent years, hyperthermia therapy in conjunction with intravesical therapy has been gaining traction as a treatment option for bladder cancer, especially if Bacillus Calmette-Guerin might not be available. Trials of intravesical chemotherapy with heat are few and there has been considerable heterogeneity between studies. However, multiple new trials have accrued and high-quality data are forthcoming. In this review, we discuss the role of combined intravesical hyperthermia and chemotherapy as a novel approach for the treatment of bladder cancer.

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10.1016/j.ucl.2019.09.008

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Tan, Wei Phin, Thomas A Longo and Brant A Inman (2020). Heated Intravesical Chemotherapy: Biology and Clinical Utility. The Urologic clinics of North America, 47(1). pp. 55–72. 10.1016/j.ucl.2019.09.008 Retrieved from https://hdl.handle.net/10161/24272.

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Scholars@Duke

Longo

Thomas Andrew Longo

Assistant Professor of Surgery
Inman

Brant Allen Inman

Professor of Surgery

Clinical research interests:
Clinical trials of novel diagnostic tests and therapies for genitourinary malignancies, with a strong focus on bladder cancer.

Basic science research interests:
Immune therapies for cancer, hyperthermia and heat-based treatment of cancer, molecular biology of genitourinary cancers, novel diagnostics and therapies for genitourinary cancers


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