Patients with a depressive and/or anxiety disorder can achieve optimum Long term outcomes after surgery for grade 1 spondylolisthesis: Analysis from the quality outcomes database (QOD).

dc.contributor.author

Kashlan, Osama

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Swong, Kevin

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Alvi, Mohammed Ali

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Bisson, Erica F

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Mummaneni, Praveen V

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Knightly, John

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Chan, Andrew

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Yolcu, Yagiz U

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Glassman, Steven

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Foley, Kevin

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Slotkin, Jonathan R

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Potts, Eric

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Shaffrey, Mark

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Shaffrey, Christopher I

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Haid, Regis W

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Fu, Kai-Ming

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Wang, Michael Y

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Asher, Anthony L

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Bydon, Mohamad

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Park, Paul

dc.date.accessioned

2023-06-20T11:56:18Z

dc.date.available

2023-06-20T11:56:18Z

dc.date.issued

2020-10

dc.date.updated

2023-06-20T11:56:18Z

dc.description.abstract

Introduction

In the current study, we sought to compare baseline demographic, clinical, and operative characteristics, as well as baseline and follow-up patient reported outcomes (PROs) of patients with any depressive and/or anxiety disorder undergoing surgery for low-grade spondylolisthesis using a national spine registry.

Patients and methods

The Quality Outcomes Database (QOD) was queried for patients undergoing surgery for Meyerding grade 1 lumbar spondylolisthesis undergoing 1-2 level decompression or 1 level fusion at 12 sites with the highest number of patients enrolled in QOD with 2-year follow-up data.

Results

Of the 608 patients identified, 25.6 % (n = 156) had any depressive and/or anxiety disorder. Patients with a depressive/anxiety disorder were less likely to be discharged home (p < 0.001). At 3=months, patients with a depressive/anxiety disorder had higher back pain (p < 0.001), lower quality of life (p < 0.001) and higher disability (p = 0.013); at 2 year patients with depression and/or anxiety had lower quality of life compared to those without (p < 0.001). On multivariable regression, depression was associated with significantly lower odds of achieving 20 % or less ODI (OR 0.44, 95 % CI 0.21-0.94,p = 0.03). Presence of an anxiety disorder was not associated with decreased odds of achieving that milestone at 3 months. The presence of depressive-disorder, anxiety-disorder or both did not have an impact on ODI at 2 years. Finally, patient satisfaction at 2-years did not differ between the two groups (79.8 % vs 82.7 %,p = 0.503).

Conclusion

We found that presence of a depressive-disorder may impact short-term outcomes among patients undergoing surgery for low grade spondylolisthesis but longer term outcomes are not affected by either a depressive or anxiety disorder.
dc.identifier

S0303-8467(20)30441-8

dc.identifier.issn

0303-8467

dc.identifier.issn

1872-6968

dc.identifier.uri

https://hdl.handle.net/10161/28153

dc.language

eng

dc.publisher

Elsevier BV

dc.relation.ispartof

Clinical neurology and neurosurgery

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10.1016/j.clineuro.2020.106098

dc.subject

Humans

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Spondylolisthesis

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Treatment Outcome

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Spinal Fusion

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Reoperation

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Risk Factors

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Anxiety Disorders

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Depressive Disorder

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Quality of Life

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Databases, Factual

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Aged

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Middle Aged

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Patient Satisfaction

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Female

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Male

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Patient Reported Outcome Measures

dc.title

Patients with a depressive and/or anxiety disorder can achieve optimum Long term outcomes after surgery for grade 1 spondylolisthesis: Analysis from the quality outcomes database (QOD).

dc.type

Journal article

duke.contributor.orcid

Shaffrey, Christopher I|0000-0001-9760-8386

pubs.begin-page

106098

pubs.organisational-group

Duke

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School of Medicine

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Clinical Science Departments

pubs.organisational-group

Orthopaedic Surgery

pubs.organisational-group

Neurosurgery

pubs.publication-status

Published

pubs.volume

197

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