Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations

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Published Version (Please cite this version)

10.1158/1078-0432.CCR-18-1116

Publication Info

Kugel, Curtis H, Stephen M Douglass, Marie R Webster, Amanpreet Kaur, Qin Liu, Xiangfan Yin, Sarah A Weiss, Farbod Darvishian, et al. (n.d.). Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations. Clinical Cancer Research. 10.1158/1078-0432.CCR-18-1116 Retrieved from https://hdl.handle.net/10161/17350.

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Scholars@Duke

Al-Rohil

Rami Nayef Al-Rohil

Associate Professor of Pathology

I am dermatopathologist with special interest in melanocytic pathology (including molecular alterations and tests that aid in predicting their biologic behavior), and soft tissue pathology

Conejo-Garcia

Jose Ramon Conejo-Garcia

Professor in Integrative Immunobiology

Jose Conejo-Garcia’s research program focuses on understanding and targeting the mechanisms governing the balance between immunosuppression and protective immunity in the tumor microenvironment, with an emphasis on the crosstalk between innate (gamma/delta) and adaptive (alpha/beta) T cells, and B lymphocytes, including in Tertiary Lymphoid Structures. Discoveries for the Conejo-Garcia lab are also being translated in active clinical trials using CAR T cells to treat ovarian cancer patients. 


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