Generating evidence for therapeutic effects: the need for well-conducted randomized trials.

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2020-12-03

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Abstract

In this viewpoint, Robert Califf, former commissioner of the U.S. Food and Drug Administration, and colleagues reflect on how to approach questions about which patient treatments and strategies work, particularly in light of the tremendous pressure on the government and biomedical research enterprise to quickly develop safe, effective therapies during the SARS-CoV-2 pandemic.

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Published Version (Please cite this version)

10.1172/jci146391

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Califf, Robert M, Lesley H Curtis, Robert A Harrington, Adrian F Hernandez and Eric D Peterson (2020). Generating evidence for therapeutic effects: the need for well-conducted randomized trials. The Journal of clinical investigation. 10.1172/jci146391 Retrieved from https://hdl.handle.net/10161/22009.

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