Genetic mapping of brain plasticity across development in Williams syndrome: ERP markers of face and language processing.

dc.contributor.author

Mills, DL

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Dai, L

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Fishman, I

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Yam, A

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Appelbaum, LG

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St George, M

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Galaburda, A

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Bellugi, U

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Korenberg, JR

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England

dc.date.accessioned

2017-01-31T19:02:44Z

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2013

dc.description.abstract

In Williams Syndrome (WS), a known genetic deletion results in atypical brain function with strengths in face and language processing. We examined how genetic influences on brain activity change with development. In three studies, event-related potentials (ERPs) from large samples of children, adolescents, and adults with the full genetic deletion for WS were compared to typically developing controls, and two adults with partial deletions for WS. Studies 1 and 2 identified ERP markers of brain plasticity in WS across development. Study 3 suggested that, in adults with partial deletions for WS, specific genes may be differentially implicated in face and language processing.

dc.identifier

http://www.ncbi.nlm.nih.gov/pubmed/24219698

dc.identifier.eissn

1532-6942

dc.identifier.uri

https://hdl.handle.net/10161/13527

dc.language

eng

dc.publisher

Informa UK Limited

dc.relation.ispartof

Dev Neuropsychol

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10.1080/87565641.2013.825617

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Adolescent

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Adult

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Brain

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Child

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Electroencephalography

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Evoked Potentials

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Face

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Female

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Humans

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Language

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Male

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Mental Processes

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Reaction Time

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Recognition (Psychology)

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Speech Perception

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Williams Syndrome

dc.title

Genetic mapping of brain plasticity across development in Williams syndrome: ERP markers of face and language processing.

dc.type

Journal article

duke.contributor.orcid

Appelbaum, LG|0000-0002-3184-6725

pubs.author-url

http://www.ncbi.nlm.nih.gov/pubmed/24219698

pubs.begin-page

613

pubs.end-page

642

pubs.issue

8

pubs.organisational-group

Clinical Science Departments

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Duke

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Duke Institute for Brain Sciences

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Duke Science & Society

pubs.organisational-group

Initiatives

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Institutes and Provost's Academic Units

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Psychiatry & Behavioral Sciences

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Psychiatry & Behavioral Sciences, Brain Stimulation and Neurophysiology

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School of Medicine

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University Institutes and Centers

pubs.publication-status

Published

pubs.volume

38

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