Association of Race and Ethnicity with Genomic Testing at a Comprehensive Cancer Center in North Carolina.
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2024-11
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Non-Hispanic Black patients diagnosed with prostate cancer between 2014 and 2019 and treated at a comprehensive cancer center were less likely to use tumor-specific genomic testing compared with non-Hispanic White patients. Disparities in the use of precision oncology technologies should be monitored and addressed to ensure equitable cancer care.Type
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Meernik, Clare, Frances Wang, Yadurshini Raveendran, Michelle F Green, Devon K Check, Hayden B Bosworth, Linda M Sutton, John H Strickler, et al. (2024). Association of Race and Ethnicity with Genomic Testing at a Comprehensive Cancer Center in North Carolina. Cancer research communications, 4(11). pp. 2968–2975. 10.1158/2767-9764.crc-24-0134 Retrieved from https://hdl.handle.net/10161/33918.
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Scholars@Duke
Clare Meernik
Clare Meernik, PhD, MPH is a Research Assistant Professor at the Kenneth H. Cooper Institute at Texas Tech University Health Sciences Center and an Adjunct Assistant Professor at Duke University School of Medicine. She is an epidemiologist with expertise in chronic disease prevention, cancer survivorship, and healthy aging. Her research focuses on disease prevention and healthy aging through lifestyle-based strategies.
Dr. Meernik has authored more than 55 peer-reviewed manuscripts in journals including JAMA, BMJ, Pediatrics, Human Reproduction, and Tobacco Control. Her research spans topics such as cancer epidemiology and survivorship, tobacco prevention and control, cardiorespiratory fitness, and aging.
She was previously awarded an F31 predoctoral fellowship from the National Cancer Institute and was a T32 Fellow in the Cancer Control Education Program at the University of North Carolina at Chapel Hill (UNC). She also completed the Physical Activity and Public Health (PAPH) Research Course at the University of South Carolina.
Prior to her current role, Dr. Meernik was a Postdoctoral Fellow in the Duke University School of Medicine and a Research Specialist with the Tobacco Prevention and Evaluation Program at the UNC Department of Family Medicine. She earned her PhD in Epidemiology from the UNC Gillings School of Global Public Health and her MPH in Epidemiology from the University of Michigan School of Public Health.
Devon Karnes Check
Devon Check, PhD is a health services and implementation researcher whose primary research interests include quality of care and the implementation of evidence-based and guideline-recommended practices in oncology. Her projects use large secondary data analysis as well as qualitative and mixed methods to investigate variation and inequities in cancer care, the experiences of patients and clinicians, and multi-level factors that impact cancer treatment and outcomes. She has a specific interest in supportive cancer care, and within that area, she has a growing portfolio of research projects focused on pain and symptom management in cancer.
Dr. Check also has methodological expertise in implementation science. She has served as the implementation research methods expert on several behavioral intervention trials that use a hybrid effectiveness-implementation design. She also co-leads the Implementation Science Core Working Group as part of the Coordinating Center for the NIH Pragmatic Trials Collaboratory and the NIH HEAL Collaboratory.
Dr. Check received her PhD in Health Policy and Management from the Gillings School of Global Public Health at UNC-Chapel Hill. Prior to joining the Department of Population Health Sciences at Duke, she completed a postdoctoral fellowship in Delivery Science at Kaiser Permanente Northern California's Division of Research.
Areas of Expertise: Implementation Science and Health Services Research
Hayden Barry Bosworth
Dr. Bosworth is a health services researcher and Deputy Director of the Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT) at the Durham VA Medical Center. He is also Vice Chair of Education and Professor of Population Health Sciences. He is also a Professor of Medicine, Psychiatry, and Nursing at Duke University Medical Center and Adjunct Professor in Health Policy and Administration at the School of Public Health at the University of North Carolina at Chapel Hill. His research interests comprise three overarching areas of research: 1) clinical research that provides knowledge for improving patients’ treatment adherence and self-management in chronic care; 2) translation research to improve access to quality of care; and 3) eliminate health care disparities.
Dr. Bosworth is the recipient of an American Heart Association established investigator award, the 2013 VA Undersecretary Award for Outstanding Achievement in Health Services Research (The annual award is the highest honor for VA health services researchers), and a VA Senior Career Scientist Award. In terms of self-management, Dr. Bosworth has expertise developing interventions to improve health behaviors related to hypertension, coronary artery disease, and depression, and has been developing and implementing tailored patient interventions to reduce the burden of other chronic diseases. These trials focus on motivating individuals to initiate health behaviors and sustaining them long term and use members of the healthcare team, particularly pharmacists and nurses. He has been the Principal Investigator of over 30 trials resulting in over 400 peer reviewed publications and four books. This work has been or is being implemented in multiple arenas including Medicaid of North Carolina, private payers, The United Kingdom National Health System Direct, Kaiser Health care system, and the Veterans Affairs.
Areas of Expertise: Health Behavior, Health Services Research, Implementation Science, Health Measurement, and Health Policy
John Strickler
John Strickler, MD is a Professor of Medicine in the Division of Medical Oncology, where he is Co-Leader for the Precision Cancer Medicine and Investigational Therapeutics Program at the Duke Cancer Institute, Leader of the Molecular Tumor Board, and Associate Director of Clinical Research – GI Oncology. Dr. Strickler’s clinic specializes on the treatment of gastrointestinal malignancies, with a particular emphasis on gastroesophageal, pancreatic, and colorectal cancers. His research focuses on precision cancer medicine: identification of biomarkers that predict sensitivity or resistance to targeted therapies and immunotherapy. He has designed and executed clinical trials that test novel therapies and innovative therapeutic strategies. He was Principal Investigator on an investigator sponsored trial that led to the first FDA-approved therapy for HER2+ metastatic colorectal cancer. He has first-author publications in several high impact factor medical journals, including the New England Journal of Medicine, Clinical Cancer Research, Cancer Discovery, Journal of Clinical Oncology, and Lancet Oncology. Nationally, he has served as a member of the American Society of Clinical Oncology (ASCO) Treatment Guidelines Committee for Advanced Colon Cancer.
Tomi Akinyemiju
Area of Expertise: Epidemiology
Dr. Akinyemiju is a Professor of Population Health Sciences, Global Health and Ob/Gyn with expertise in cancer epidemiology, cancer biology, global health, and health disparities. Her research expertise and accomplishments have focused on articulating and innovating conceptual and empirical approaches for cancer health disparities research, specifically, disentangling the role of race as a social construct and race-associated biological mechanisms that contribute to cancer disparities. Dr. Akinyemiju’s leadership centers around building cross-enterprise, multi-stakeholder coalitions to advance health equity, promote inclusion and diversity, and mentor the next generation of diverse, talented clinical research scholars. Dr. Akinyemiju has received numerous awards, including the 2023 Michelle Winn Inclusive Excellence Award
Dr. Akinyemiju has published over 180 peer-reviewed publications, and her research program has been continuously funded by the National Institutes of Health, Susan G. Komen and the V Foundation. She has mentored (formally and informally) over 70 trainees and junior faculty, over 50% of whom are URM. Dr. Akinyemiju works extensively with diverse stakeholders, including community-based organizations, policy makers, providers, health system leadership, and leaders from diverse communities to develop impactful, evidence-based interventions to advance health equity
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