Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation.
| dc.contributor.author | Freedman, Neil J | |
| dc.contributor.author | Lefkowitz, Robert J | |
| dc.coverage.spatial | United States | |
| dc.date.accessioned | 2012-10-24T18:31:58Z | |
| dc.date.issued | 2004-05 | |
| dc.description.abstract | Antibodies specific for the beta(1)-adrenergic receptor are found in patients with chronic heart failure of various etiologies. From work presented in this issue of the JCI, we can now infer that these antibodies actually contribute to the pathogenesis of chronic heart failure. This commentary discusses mechanisms by which these antibodies may engender cardiomyopathy. | |
| dc.identifier | ||
| dc.identifier.issn | 0021-9738 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.publisher | American Society for Clinical Investigation | |
| dc.relation.ispartof | J Clin Invest | |
| dc.relation.isversionof | 10.1172/JCI21748 | |
| dc.relation.journal | Journal of Clinical Investigation | |
| dc.subject | Adrenergic beta-Antagonists | |
| dc.subject | Autoantibodies | |
| dc.subject | Heart Failure | |
| dc.subject | Humans | |
| dc.subject | Models, Cardiovascular | |
| dc.subject | Myocardium | |
| dc.subject | Receptors, Adrenergic, beta-1 | |
| dc.title | Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation. | |
| dc.type | Journal article | |
| duke.contributor.orcid | Freedman, Neil J|0000-0002-8593-8676 | |
| duke.contributor.orcid | Lefkowitz, Robert J|0000-0003-1472-7545 | |
| duke.description.issue | 10 | |
| duke.description.volume | 113 | |
| pubs.author-url | ||
| pubs.begin-page | 1379 | |
| pubs.end-page | 1382 | |
| pubs.issue | 10 | |
| pubs.organisational-group | Basic Science Departments | |
| pubs.organisational-group | Biochemistry | |
| pubs.organisational-group | Cell Biology | |
| pubs.organisational-group | Chemistry | |
| pubs.organisational-group | Clinical Science Departments | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | Duke Cancer Institute | |
| pubs.organisational-group | Institutes and Centers | |
| pubs.organisational-group | Medicine | |
| pubs.organisational-group | Medicine, Cardiology | |
| pubs.organisational-group | Pathology | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | Trinity College of Arts & Sciences | |
| pubs.publication-status | Published | |
| pubs.volume | 113 |
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