Dengue Myocarditis: A Case Report and Major Review.


Dengue is a viral disease transmitted by the bite of a female arthropod, prevalent primarily in tropical and subtropical regions. Its manifestations include asymptomatic infections, dengue fever, and a severe form called hemorrhagic dengue or dengue shock syndrome. Atypical manifestations can also occur, called expanded dengue syndrome. We describe the case of a 43-year-old man with an unusual presentation of dengue, demonstrating a workup suggestive of myocardial and pericardial damage. Symptoms and markers indicative of cardiac compromise improved after five days on anti-inflammatory treatment. Dengue myocarditis is considered an uncommon complication of dengue, although its reported incidence is likely an underestimation. In general, most cases of dengue myocarditis are self-limited, with only a minority at risk of progressing to heart failure. In order to improve recognition and prevent progression, healthcare providers should maintain a high degree of suspicion regarding potential cardiac complications in patients with dengue.





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Publication Info

Cristodulo, Roberto, Gracia Luoma-Overstreet, Fernando Leite, Manuel Vaca, Michelle Navia, Gustavo Durán, Fernando Molina, Bozorg Zonneveld, et al. (2023). Dengue Myocarditis: A Case Report and Major Review. Global heart, 18(1). p. 41. 10.5334/gh.1254 Retrieved from

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N. Alejandro (Alex) Barbagelata

Adjunct Professor in the Department of Medicine

Medical degree at the University of Buenos Aires. Residency/Cardiology Fellowship at the Sanatorio Guemes/Favaloro Foundation. Cardiac cath fellow at the Sanatorio Guemes. International Scholar in Artificial Organs at the Cleveland Clinic. Duke Clinical Research Institute research fellow.

Faculty member in the Cardiology Division at the University of Texas Medical Branch with the rank of Assoc Professor of Medicine as CCU and Cardiac Cath Lab attending (invasive cardiologist) on all type of cardiovascular diseases Director or Associated Dir of the Advanced Heart Failure that included devices such as aquapheresis, 2.5 impella, Cardiac Power, and surgical such as being part of the approval team for destination therapy on Heart Mate II. UNOS primary physician in the Heart Transplant program 2011-2013. Current Adj Ast Professor Medicine/Cardiology at Duke University, member of the Board of Directors of DUCCS (a Duke Clinical Research organization). Director of the Advanced Heart Failure Postgraduate Program at the Universidad Catolica Argentina (UCA). Staff member Interventional Cardiology service at the Instituto del diagnostico y tratamiento, Buenos Aires, Argentina. 

Research Interest in Acute Myocardial Infarction and Heart Failure, percutaneous and surgical devices in heart failure. Early identification of STEMI such as criteria's for MI in LBBB ('s_criteria), new descriptors in Q wave/non Q wave, use of telemedicine for timeliness reperfusion. Co-editor of the book on “prehospital Management of Acute Myocardial Infarction” Member of the Int. Speaker Bureau AHA. Published more than 60 peer articles and more than 100 hundred abstract and speaker in a number of Scientific Meetings.

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