Should Sagittal Spinal Alignment Targets for Adult Spinal Deformity Correction Depend on Pelvic Incidence and Age?

dc.contributor.author

Protopsaltis, Themistocles S

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Soroceanu, Alexandra

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Tishelman, Jared C

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Buckland, Aaron J

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Mundis, Gregory M

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Smith, Justin S

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Daniels, Alan

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Lenke, Lawrence G

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Kim, Han Jo

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Klineberg, Eric O

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Ames, Christopher P

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Hart, Robert A

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Bess, Shay

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Shaffrey, Christopher I

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Schwab, Frank J

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Lafage, Virginie

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International Spine Study Group (ISSG)

dc.date.accessioned

2023-06-20T12:11:19Z

dc.date.available

2023-06-20T12:11:19Z

dc.date.issued

2020-02

dc.date.updated

2023-06-20T12:11:13Z

dc.description.abstract

Study design

Retrospective analysis.

Objective

Determine whether deformity corrections should vary by pelvic incidence (PI).

Summary of background data

Alignment targets for deformity correction have been reported for various radiographic parameters. The T1 pelvic-angle (TPA) has gained in applications for adult spinal deformity (ASD) surgical-planning since it directly measures spinal alignment separate from pelvic- and lower-extremity compensation. Recent studies have demonstrated that ASD corrections should be age specific.

Methods

A prospective database of consecutive ASD patients was analyzed in conjunction with a normative spine database. Clinical measures of disability included the Oswestry Disability Index (ODI) and Short Form 36 Survey (SF-36) Physical Component Score (PCS). Baseline relationships between TPA, age, PI, and ODI/SF-36 PCS scores were analyzed in the ASD and asymptomatic patients. Linear regression modeling was used to determine alignment targets based on PI and age-specific normative SF-36-PCS values.

Results

Nine hundred three ASD patients (mean 53.7 yr) and 111 normative subjects (mean 50.7 yr) were included. Patients were subanalyzed by PI: low, medium, high (<40, 40-75, >75); and age: elderly (>65 yr, n = 375), middle age (45-65 yr, n = 387), and young (18-45 yr, n = 141). TPA and SRS-Schwab parameters correlated with age and PI in ASD and normative subjects (r = 0.42, P < 0.0001). ODI correlated with PCS (r = 0.71, P < 0.0001). Linear regression analysis using age-normative SF-36-PCS values demonstrated that ideal spinopelvic alignment is less strict with increasing PI and age.

Conclusion

Targets for ASD correction should vary by age and PI. This is demonstrated in both asymptomatic and ASD subjects. Using age-normative SF-36 PCS values, alignment targets are described for different age and PI categories. High-PI patients do not require as rigorous realignments to attain age-specific normative levels of health status. As such, sagittal spinal alignment targets increase with increasing age as well as PI.

Level of evidence

3.
dc.identifier

00007632-202002150-00009

dc.identifier.issn

0362-2436

dc.identifier.issn

1528-1159

dc.identifier.uri

https://hdl.handle.net/10161/28161

dc.language

eng

dc.publisher

Ovid Technologies (Wolters Kluwer Health)

dc.relation.ispartof

Spine

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10.1097/brs.0000000000003237

dc.subject

International Spine Study Group (ISSG)

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Pelvic Bones

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Humans

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Spinal Diseases

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Incidence

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Retrospective Studies

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Prospective Studies

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Age Factors

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Health Status

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Quality of Life

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Databases, Factual

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Adolescent

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Adult

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Aged

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Middle Aged

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Female

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Male

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Young Adult

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Surveys and Questionnaires

dc.title

Should Sagittal Spinal Alignment Targets for Adult Spinal Deformity Correction Depend on Pelvic Incidence and Age?

dc.type

Journal article

duke.contributor.orcid

Shaffrey, Christopher I|0000-0001-9760-8386

pubs.begin-page

250

pubs.end-page

257

pubs.issue

4

pubs.organisational-group

Duke

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School of Medicine

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Clinical Science Departments

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Orthopaedic Surgery

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Neurosurgery

pubs.publication-status

Published

pubs.volume

45

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