Idiopathic Megaduodenum in a Teenager: A Case Report.
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2024-01
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Abstract
Megaduodenum is a rare clinical syndrome characterized by significant duodenal dilation, elongation, and hypertrophy. Given its rarity and nonspecific clinical manifestations, megaduodenum may be misdiagnosed, leading to delays in surgical care and increased morbidity. We describe a case of idiopathic megaduodenum in a teenage Caucasian female, who presented with a five-year history of halitosis, recurrent belching, bloating, nausea and vomiting, and postprandial epigastric abdominal pain. She was diagnosed with megaduodenum by dramatic findings on contrast radiography. She developed a duodenal volvulus necessitating emergency exploratory laparotomy, during which a duodenal plication and a side-to-side duodenojejunostomy were performed. Exploratory laparotomy and histopathological analysis were unrevealing of any definitive abnormalities to explain her megaduodenum. Postoperatively, she developed two early small bowel obstructions, both from subsequent adhesions requiring repeat laparotomy with adhesiolysis. She has subsequently recovered without incident. Diagnosis and accurate classification of megaduodenum requires surgical exploration with a full-thickness biopsy and subsequent histopathologic analysis to rule out obstructive or functional disorders of the duodenum. Treatment of megaduodenum depends on the underlying cause and degree of duodenal distention. It is crucial that clinicians are knowledgeable of the various surgical options, their indications, and the potential postoperative complications that may arise.
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Eze, Anthony N, Akachukwu N Eze, Chinecherem M Chime, Fengming Chen, Dimitrios Moris, Robin Schmitz and Tamara N Fitzgerald (2024). Idiopathic Megaduodenum in a Teenager: A Case Report. Cureus, 16(1). p. e51930. 10.7759/cureus.51930 Retrieved from https://hdl.handle.net/10161/30204.
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Scholars@Duke
Fengming Chen
Tamara Noel Fitzgerald
My academic interest is global pediatric surgery. There are millions of children worldwide who do not have access to safe surgery for congenital anomalies and acquired conditions. As a result, many children in low-middle income countries live with chronic disability or die before they can access surgical care. In many cultures, congenital problems may also lead to social isolation or catastrophic health expenditure for families.
Many countries in sub-Saharan Africa have just a handful of qualified surgeons. For example, in Uganda, the country where I have most frequently worked, there are 4 general pediatric surgeons for a country of 39 million people. This would be the equivalent of 32 pediatric surgeons serving the entire United States. There are neighboring countries with no pediatric surgeons.
My work focuses on surgical capacity building - empowering and working with local surgeons in low-middle income countries to increase numbers of surgical providers, improve quality and increase surgical support services such as intensive care and anesthesia services. I have several ongoing projects regarding the burden of surgical disease for patients and their families in low-middle income countries, surgical training and capacity building.
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