Idiopathic Megaduodenum in a Teenager: A Case Report.

dc.contributor.author

Eze, Anthony N

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Eze, Akachukwu N

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Chime, Chinecherem M

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Chen, Fengming

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Moris, Dimitrios

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Schmitz, Robin

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Fitzgerald, Tamara N

dc.date.accessioned

2024-03-01T14:34:30Z

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2024-03-01T14:34:30Z

dc.date.issued

2024-01

dc.description.abstract

Megaduodenum is a rare clinical syndrome characterized by significant duodenal dilation, elongation, and hypertrophy. Given its rarity and nonspecific clinical manifestations, megaduodenum may be misdiagnosed, leading to delays in surgical care and increased morbidity. We describe a case of idiopathic megaduodenum in a teenage Caucasian female, who presented with a five-year history of halitosis, recurrent belching, bloating, nausea and vomiting, and postprandial epigastric abdominal pain. She was diagnosed with megaduodenum by dramatic findings on contrast radiography. She developed a duodenal volvulus necessitating emergency exploratory laparotomy, during which a duodenal plication and a side-to-side duodenojejunostomy were performed. Exploratory laparotomy and histopathological analysis were unrevealing of any definitive abnormalities to explain her megaduodenum. Postoperatively, she developed two early small bowel obstructions, both from subsequent adhesions requiring repeat laparotomy with adhesiolysis. She has subsequently recovered without incident. Diagnosis and accurate classification of megaduodenum requires surgical exploration with a full-thickness biopsy and subsequent histopathologic analysis to rule out obstructive or functional disorders of the duodenum. Treatment of megaduodenum depends on the underlying cause and degree of duodenal distention. It is crucial that clinicians are knowledgeable of the various surgical options, their indications, and the potential postoperative complications that may arise.

dc.identifier.issn

2168-8184

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2168-8184

dc.identifier.uri

https://hdl.handle.net/10161/30204

dc.language

eng

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Springer Science and Business Media LLC

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Cureus

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10.7759/cureus.51930

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https://creativecommons.org/licenses/by-nc/4.0

dc.subject

duodenal volvulus

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idiopathic

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malnutrition

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megaduodenum

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small bowel obstruction

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superior mesenteric artery syndrome

dc.title

Idiopathic Megaduodenum in a Teenager: A Case Report.

dc.type

Journal article

duke.contributor.orcid

Chen, Fengming|0000-0002-6406-0948

pubs.begin-page

e51930

pubs.issue

1

pubs.organisational-group

Duke

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School of Medicine

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Clinical Science Departments

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Pathology

pubs.publication-status

Published

pubs.volume

16

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