Transplant Drug Interactions and a Word of Caution for the HIV Provider. A Case Report.
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2018-04-05
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Abstract
Electronic medical record platforms fail to support provider alerts when a drug is discontinued. Protease inhibitors, often boosted by ritonavir or cobicistat, increase the serum concentration of calcineurin inhibitors. This case demonstrates acute liver transplant rejection in an HIV-positive recipient due to a failure to recognize the loss of protease inhibitor interaction with his immunosuppressive regimen.
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Hemmersbach-Miller, Marion, Carl L Berg, Julia A Messina and Cameron R Wolfe (2018). Transplant Drug Interactions and a Word of Caution for the HIV Provider. A Case Report. Open forum infectious diseases, 5(4). p. ofy070. 10.1093/ofid/ofy070 Retrieved from https://hdl.handle.net/10161/18164.
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Scholars@Duke
Carl Berg
Julia Antoinette Messina
I am a Transplant Infectious Diseases Physician who specializes in the care of immunocompromised patients including solid organ and bone marrow transplant recipients and patients with HIV. My research interests are in infections and clinical outcomes in patients with hematologic malignancies.
Cameron Robert Wolfe
HIV infection, Transplant-related infectious diseases, general infectious diseases, Biological and Emergency Preparedness for hospital systems, influenza and respiratory viral pathogens
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