Browsing by Subject "Adult congenital heart disease"

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    Extra-cardiac manifestations of adult congenital heart disease.
    (Trends Cardiovasc Med, 2016-10) Gaeta, Stephen A; Ward, Cary; Krasuski, Richard A
    Advancement in correction or palliation of congenital cardiac lesions has greatly improved the lifespan of congenital heart disease patients, resulting in a rapidly growing adult congenital heart disease (ACHD) population. As this group has increased in number and age, emerging science has highlighted the systemic nature of ACHD. Providers caring for these patients are tasked with long-term management of multiple neurologic, pulmonary, hepatic, renal, and endocrine manifestations that arise as syndromic associations with congenital heart defects or as sequelae of primary structural or hemodynamic abnormalities. In this review, we outline the current understanding and recent research into these extra-cardiac manifestations.
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    Heart Transplantation and Mechanical Circulatory Support in Adults with Congenital Heart Disease.
    (Current cardiology reports, 2018-08-09) Serfas, John D; Patel, Priyesh A; Krasuski, Richard A
    PURPOSE OF REVIEW:To assess current management strategies for advanced heart failure in adults with congenital heart disease, including heart transplantation and mechanical circulatory support. RECENT FINDINGS:Current data demonstrate that adults with CHD generally experience higher short-term mortality after heart transplantation and MCS implantation, but enjoy superior long-term survival. Such patients are nonetheless less likely to receive a transplant than non-ACHD peers due to a variety of factors, including lack of applicability of current listing criteria to HF in ACHD. MCS is underutilized in ACHD, but provides similar quality of life benefits for ACHD and non-ACHD patients alike. Heart failure in ACHD is complex and difficult to treat, and both heart transplantation and mechanical circulatory support are often challenging to implement in this patient population. However, long-term results are encouraging, and existing data supports increasing use of MCS and transplant earlier in their disease course. Multidisciplinary care is critical to success in these complex patients.
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    Uncorrected Tetralogy of Fallot, Biventricular Dysfunction, and a Large Pericardial Effusion.
    (J Cardiothorac Vasc Anesth, 2015-10) McCartney, Sharon L; Machovec, Kelly; Jooste, Edmund H