Browsing by Subject "Computers"
Results Per Page
Sort Options
Item Open Access Automatic segmentation of seven retinal layers in SDOCT images congruent with expert manual segmentation.(Opt Express, 2010-08-30) Chiu, SJ; Li, XT; Nicholas, P; Toth, CA; Izatt, JA; Farsiu, SSegmentation of anatomical and pathological structures in ophthalmic images is crucial for the diagnosis and study of ocular diseases. However, manual segmentation is often a time-consuming and subjective process. This paper presents an automatic approach for segmenting retinal layers in Spectral Domain Optical Coherence Tomography images using graph theory and dynamic programming. Results show that this method accurately segments eight retinal layer boundaries in normal adult eyes more closely to an expert grader as compared to a second expert grader.Item Open Access Compiling Inequalities: Computerization in the British Civil Service and Nationalized Industries, 1940-1979(2009) Hicks, MarieIn the 1950s and early 1960s, Great Britain's computing industry led the world in the development and application of computers for business and administrative work. The British government and civil service, paragons of meritocracy in a country stratified by class, committed themselves to implementing computerized data processing techniques throughout the sprawling public sector, in order to modernize their economy, maintain the competitiveness of British high-technology industries, and reconsolidate the nation's strength and reputation worldwide. To succeed in this project, the British government would need to leverage the country's existing expertise, cultivate the heterogeneous field of computing manufacturers, and significantly re-train labor.
By the 1970s, Britain's early lead in the field of computing had evaporated, government computing projects had produced disappointing results, and the nation's status as a world power had declined precipitously. This dissertation seeks to explain why British computing achieved so few of its intended results by looking at the intractable labor problems within the public sector during the heyday of the Britain's proclaimed "technological revolution." The dissertation argues that the interpretation of, and solutions for, these labor problems produced disastrous effects.
Sources used include government documents, civil service records, records of the nationalized industries (the Post Office, National Health Service, Central Electricity Generating Board, Coal Industry, Railways, and others), computing industry records, press accounts, and oral interviews. By using methodologies from the history of technology, institutional history, and labor history, as well as gender analysis, this dissertation shows that despite the government's commitment to both high technology usage and labor meritocracy, competing claims of technological expertise and management tradition led the government to misjudge the role of computing within the public sector and the nation.
Beginning with a labor situation in which women did the majority of computing work, and seeking to achieve a situation in which young men and management-level technocrats tightly controlled all digital computing, the British government over-centralized its own computing endeavors, and the nation's computing industry, leading to a dangerous winnowing of skill and expertise within the already-small field. The eventual takeover of the British computing market by IBM, and purchase of the last viable British computing company by Fujitsu, marked the end of any hope for Britain's computing dominance in either their home market or the global market.
While multiple factors contributed to the failures of government computing and the British computing industry--including, but not limited to, American competition, inability to effectively create a global market for British machines, and misjudging the public sector's computing needs--this dissertation argues that labor problems, arising largely from gendered concerns about technological change and power, constituted a critical, and unrecognized, stumbling block for Britain's government-led computing revolution.
Item Open Access Magnetophoretic circuits for digital control of single particles and cells.(Nat Commun, 2014-05-14) Lim, B; Reddy, V; Hu, X; Kim, K; Jadhav, M; Abedini-Nassab, R; Noh, Y; Lim, YT; Yellen, BB; Kim, CThe ability to manipulate small fluid droplets, colloidal particles and single cells with the precision and parallelization of modern-day computer hardware has profound applications for biochemical detection, gene sequencing, chemical synthesis and highly parallel analysis of single cells. Drawing inspiration from general circuit theory and magnetic bubble technology, here we demonstrate a class of integrated circuits for executing sequential and parallel, timed operations on an ensemble of single particles and cells. The integrated circuits are constructed from lithographically defined, overlaid patterns of magnetic film and current lines. The magnetic patterns passively control particles similar to electrical conductors, diodes and capacitors. The current lines actively switch particles between different tracks similar to gated electrical transistors. When combined into arrays and driven by a rotating magnetic field clock, these integrated circuits have general multiplexing properties and enable the precise control of magnetizable objects.Item Open Access Willingness of Patients to Use Computers for Health Communication and Monitoring Following Myocardial Infarction.(Computers, informatics, nursing : CIN, 2015-09) Shaw, Ryan J; Zullig, Leah L; Crowley, Matthew J; Grambow, Steven C; Lindquist, Jennifer H; Shah, Bimal R; Peterson, Eric; Bosworth, Hayden BWe describe the computer use characteristics of 406 post-myocardial infarction (MI) patients and their willingness to engage online for health communication and monitoring. Most participants were computer users (n = 259; 63.8%) and half (n = 209; 51.5%) read health information online at least monthly. However, most participants did not go online to track health conditions (n = 283; 69.7%), look at medical records (n = 287; 70.7%), or e-mail doctors (n = 351; 86.5%). Most participants would consider using a Web site to e-mail doctors (n = 275; 67.7%), share medical information with doctors (n = 302; 74.4%), send biological data to their doctor (n = 308; 75.9%), look at medical records (n = 321; 79.1%), track health conditions (n = 331; 81.5%), and read about health conditions (n = 332; 81.8%). Sharing health information online with family members (n = 181; 44.6%) or for support groups (n = 223; 54.9%) was not of much interest. Most post-MI participants reported they were interested in communicating with their provider and tracking their health conditions online. Because patients with a history of MI tend to be older and are disproportionately minority, researchers and clinicians must be careful to design interventions that embrace post-MI patients of diverse backgrounds that both improve their access to care and health outcomes.