Browsing by Subject "Friction"
Results Per Page
Sort Options
Item Open Access Cartilage Lubrication and Joint Protection by the Glycoprotein PRG4 Studied on the Microscale(2010) Coles, Jeffrey MichaelHuman joints are able to withstand millions of loading cycles with loads regularly more than 3 times an individual's body weight in large part due to the unique bearing properties of articular cartilage, a strong, slippery tissue that covers the ends of long bones. PRG4 is a boundary lubricating glycoprotein present on the cartilage surface and in the synovial fluid surrounding it. While evidence that PRG4 lubricates and preserves normal joint function is strong, little is known of its effect on cartilage surface properties, the mechanism by which it lubricates, or its postulated role of preventing wear on joints. The effect of PRG4 on cartilage friction, wear, structure, morphology, and the mechanisms by which it mediates these factors are studied here. Methods to study these parameters at the microscale using atomic force microscopy are also developed.
Cartilage of mice with the Prg4 gene (which expresses PRG4) deleted is shown to be different in a number of ways from wild type cartilage. The uppermost layer is thicker and less uniform and the surface is rougher and softer. There is also a loss of proteoglycans, structural components of cartilage, from the underlying superficial tissue, and apparent tissue damage in some cases. Wear in the presence of PRG4 in shown to be significantly lower than in its absence, a finding which may have direct implications for prevention and treatment of osteoarthritis. It appears that PRG4 needs to be present in solution, not merely on the cartilage surface to have this effect, indicating that adsorption properties are important for wear prevention.
Item Open Access Functional properties of cell-seeded three-dimensionally woven poly(epsilon-caprolactone) scaffolds for cartilage tissue engineering.(Tissue Eng Part A, 2010-04) Moutos, Franklin T; Guilak, FarshidArticular cartilage possesses complex mechanical properties that provide healthy joints the ability to bear repeated loads and maintain smooth articulating surfaces over an entire lifetime. In this study, we utilized a fiber-reinforced composite scaffold designed to mimic the anisotropic, nonlinear, and viscoelastic biomechanical characteristics of native cartilage as the basis for developing functional tissue-engineered constructs. Three-dimensionally woven poly(epsilon-caprolactone) (PCL) scaffolds were encapsulated with a fibrin hydrogel, seeded with human adipose-derived stem cells, and cultured for 28 days in chondrogenic culture conditions. Biomechanical testing showed that PCL-based constructs exhibited baseline compressive and shear properties similar to those of native cartilage and maintained these properties throughout the culture period, while supporting the synthesis of a collagen-rich extracellular matrix. Further, constructs displayed an equilibrium coefficient of friction similar to that of native articular cartilage (mu(eq) approximately 0.1-0.3) over the prescribed culture period. Our findings show that three-dimensionally woven PCL-fibrin composite scaffolds can be produced with cartilage-like mechanical properties, and that these engineered properties can be maintained in culture while seeded stem cells regenerate a new, functional tissue construct.Item Open Access Mesoscale Forces and Grain Motion in Granular Media Exhibiting Stick-Slip Dynamics: Effects of Friction and Grain Shape(2021) Kozlowski, Ryan HenryAn important challenge in the physics of granular materials is understanding how the properties of single grains, such as grain shape and friction, influence the mechanical strength and dynamical response of the bulk granular material. While spherical grains are often used to study granular materials in experiments and simulations, the interactions among grains, and in many cases the flow and stability of granular packings, change when grain shape is modified. In this dissertation, we explore the influence of friction and grain shape on grain-scale dynamics, properties of mesoscale force chains, and macroscopic stick-slip dynamics of granular materials through novel experiments. In one set of experiments, an intruder is pushed by a spring through an annular cell filled with a quasi-2D monolayer of photoelastic grains that either contact a glass substrate or float on water. We characterize the effects of basal friction between the substrate and grains, intergrain friction, intruder size, and grain shape on the dynamics of the intruder, the flow of grains during slip events, and spatial distribution of stresses within the granular material in stable sticking periods. In another set of experiments, a slider is pulled by a spring across a quasi-2D monolayer of gravity-packed grains set between two glass plates. We observe the influence of grain angularity on statistical properties characterizing the stick-slip dynamics of the slider as well as grain-scale dynamics and stresses.
We first compare the dynamics of the intruder driven through packings of disks that either contact the glass base -- having basal friction -- or float on water -- having no basal friction. At high packing fractions, we find that the intruder exhibits stick-slip dynamics when basal friction acts on the grains, but the intruder instead flows freely through the granular material, with only occasional sticking periods (called intermittent flow or clogging-like dynamics, quantified by the average time between sticking periods), when basal friction is removed. We also observe when basal friction is present that the intruder's dynamics transition from stick-slip to intermittent flow with decreasing packing fraction; this transition occurs at a higher packing fraction with lower intergrain friction. Lastly, in simulations that model this experimental system, we vary static and dynamic basal friction coefficients and show that dynamic basal friction, rather than static basal friction, determines whether the intruder exhibits stick-slip or intermittent flow at high packing fractions.
We next vary the size of the intruder and, at several different packing fractions for each intruder size, compute statistics of the waiting time between sticking periods, duration of sticking periods, energy released in slip events, and force of grains acting on the intruder. We show that each statistical measure for all intruder sizes collapses to a single curve when packing fraction is rescaled by the packing fraction below which the intruder carves out a completely open channel in the granular material. With a geometrical model, we relate the packing fraction of open channel formation to a characteristic packing fraction of the material and the ratio of the intruder's diameter and the width of the annular cell, and we confirm the prediction of this model.
We thirdly compare the dynamics of the intruder and grains with packings of disks and pentagons. We observe that the packing of pentagons exerts comparable forces on the intruder as the packing of disks, though at significantly lower packing fractions. We also find from the average flow fields of grains during slip events that disks circulate around the intruder and rotate about their centers of mass significantly more than pentagons, which tend to flow forward from the intruder. Lastly, using photoelasticimetry, for the packing of disks we measure a significantly larger spatial extent of stresses around the annular cell, and a significantly larger fraction of events that feature back-bending force chains, compared with the packing of pentagons.
In the last set of experiments, we vary grain angularity of a vertical (gravity-packed) granular material sheared by a slider. We observe that the average shearing force required to initiate slip events increases with angularity. As a result, sticking periods last longer and slip events release more energy in packings with more angular grains. We also observe differences in the flow fields of disks and angular grains in slip events; disks tend to form a pile in front of the slider, while other grains do not. Moreover angular grains are able to form local column-like structures at the surface of the bed that prop up the slider during sticking periods, while disks do not. We lastly show that the depth of the shear band and the depth of stress fluctuations between sticking periods are unaffected by grain angularity.
Overall, these novel observations from each experiment demonstrate that friction and grain shape are important factors determining properties of macroscopic stick-slip dynamics of granular materials, stress transmission in stable granular materials, and grain-scale dynamics during slip events. Our observations also serve as motivation for more robust modeling and theoretical descriptions of granular stability and flow more generally by considering the influences of basal friction and changes in grain shape.
Item Open Access Response of Granular Materials to Shear: Origins of Shear Jamming, Particle Dynamics, and Effects of Particle Properties(2018) Wang, DongGranular materials under shear are common in nature and industry. Previous results show changes of system behaviors when friction is added and particle shapes are varied, e.g. shear jamming for frictional grains. Understanding these changes depends on characterization of deformation induced by shear. However, previous studies mainly focus on yielding processes and are locally symmetric, e.g. shear transformation zones (STZ's). Besides, the grain scale explanation is lacking. In this thesis, I study the shear response of granular materials with various particle properties in two dimension, utilizing a novel setup that suppresses shear banding. Particles made of photoelastic materials can reveal inter-particle contact forces and be customized to have different friction and shapes. I propose novel minimum structures, trimers and branches, that account for shear jamming. These structures are locally asymmetric, which is contrary to STZ's. Systems with three different friction coefficients $\mu$ are studied: $0.15, 0.7$ and one higher than $1.7$. Shear jamming is still observed for the lowest $\mu$ studied, with the lowest value of packing fraction $\phi$ for shear jamming, $\phi_S$, increasing as $\mu$ decreases. Furthermore, these systems for all $\mu$ show abnormal diffusion under cyclic shear. The diffusion exponents show transitions as $\phi$ increases, with a $\mu$-dependent onset $\phi$. This behavior is consistent with the non-affine displacements under linear shear. In addition, systems composed of ellipses exhibit novel structural and mechanical responses different from disks, e.g., nematic ordering and local density variability under shear.
Item Open Access Transition dynamics and magic-number-like behavior of frictional granular clusters.(Phys Rev E Stat Nonlin Soft Matter Phys, 2012-07) Tordesillas, Antoinette; Walker, David M; Froyland, Gary; Zhang, Jie; Behringer, Robert PForce chains, the primary load-bearing structures in dense granular materials, rearrange in response to applied stresses and strains. These self-organized grain columns rely on contacts from weakly stressed grains for lateral support to maintain and find new stable states. However, the dynamics associated with the regulation of the topology of contacts and strong versus weak forces through such contacts remains unclear. This study of local self-organization of frictional particles in a deforming dense granular material exploits a transition matrix to quantify preferred conformations and the most likely conformational transitions. It reveals that favored cluster conformations reside in distinct stability states, reminiscent of "magic numbers" for molecular clusters. To support axial loads, force chains typically reside in more stable states of the stability landscape, preferring stabilizing trusslike, three-cycle contact triangular topologies with neighboring grains. The most likely conformational transitions during force chain failure by buckling correspond to rearrangements among, or loss of, contacts which break the three-cycle topology.