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DukeSpace is Duke University's online repository for publications and other archival materials in digital format. Dissertations and theses by Duke students since 2007 are made openly available to all here, as are many publications by Duke faculty.
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Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases. (Genetics in medicine : official journal of the American College of Medical Genetics, 2018-04)PurposeTo describe examples of missed pathogenic variants on whole-exome sequencing (WES) and the importance of deep phenotyping for further diagnostic testing.MethodsGuided by phenotypic information, three children with ...
Sister competition and birth order effects among marriage-aged girls: Evidence from a field experiment in rural Bangladesh (2018-04)Early marriage before the age of 18 is prevalent among adolescent girls in Bangladesh, but the timing of marriage is not uniform across daughters within a household, with some sisters marrying earlier than others. Using ...
(2018-06)This study builds on prior findings made in May 2018 by Chad Haefele at UNC and was conducted to evaluate targeted features of the TRLN Discovery interface and provide recommendations for future improvements and testing. ...
(2018-03)In the nineteenth century the French scientist Louis Pasteur proved that the proliferation of certain microorganisms in a host body causes most diseases. His “germ theory” catalyzed twentieth century antimicrobial attitudes, ...