Population genetic analyses reveal the African origin and strain variation of Cryptococcus neoformans var. grubii.
Type
Journal articleSubject
AfricaAnimal Migration
Animals
Columbidae
Cryptococcosis
Cryptococcus neoformans
Evolution, Molecular
Genetic Testing
Genetic Variation
Genetics, Population
Haplotypes
Humans
Phylogeny
Trees
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https://hdl.handle.net/10161/11062Published Version (Please cite this version)
10.1371/journal.ppat.1002495Publication Info
Litvintseva, Anastasia P; & Mitchell, Thomas G (2012). Population genetic analyses reveal the African origin and strain variation of Cryptococcus
neoformans var. grubii. PLoS Pathog, 8(2). pp. e1002495. 10.1371/journal.ppat.1002495. Retrieved from https://hdl.handle.net/10161/11062.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Anastasia P. Litvintseva
Adjunct Assistant Professor in the Department of Molecular Genetics and Microbiology
Thomas Greenfield Mitchell
Associate Professor Emeritus in Molecular Genetics and Microbiology
Among patients with AIDS, leukemia or other cancers, organ or bone marrow transplants,
and similar immunocompromising risk factors, the incidence of opportunistic mycoses
and the number of different fungal pathogens are increasing dramatically. For many
of these fungi, the definition of a species and the recognition of pathogen are highly
problematic. Conventional methods of identification are based on morphological and
physiological characteristics and are often time-consuming, difficult to int
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