The PsychENCODE project.
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Published Version (Please cite this version)10.1038/nn.4156
Publication InfoPsychENCODE Consortium; Akbarian, Schahram; Liu, Chunyu; Knowles, James A; Vaccarino, Flora M; Farnham, Peggy J; ... Sestan, Nenad (2015). The PsychENCODE project. Nat Neurosci, 18(12). pp. 1707-1712. 10.1038/nn.4156. Retrieved from https://hdl.handle.net/10161/13706.
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Professor in Medicine
One of my major research foci is in the genetic basis of psychiatric and neurological disorders. I am currently involved in studies to dissect the genetic etiology of attention deficit hyperactivity disorder (ADHD), autism, chiari type I malformations, essential tremor, and neural tube defects. Additional research foci include genetic modifiers of sickle cell disease, and genetic contributions to birth outcomes, particularly among African American women.
Professor in Pediatrics
My research involves identifying gene regulatory elements across the genome to help us understand how chromatin structure dictates cell function and fate. For the last 30 years, mapping chromatin accessible sites has been the gold standard method to identify the location of active regulatory elements, including promoters, enhancers, silencers, and locus control regions. I have developed technologies that can identify most DNase I hypersensitive sites from potentially any cell type from any speci
Associate Professor of Biostatistics & Bioinformatics
Professor of Biology
I study the evolution of genes and genomes with the broad aim of understanding the origins of biological diversity. My approach focuses on changes in the expression of genes using both empirical and computational approaches and spans scales of biological organization from single nucleotides through gene networks to entire genomes. At the finer end of this spectrum of scale, I am focusing on understanding the functional consequences and fitness components of specific genetic variants within reg
Alphabetical list of authors with Scholars@Duke profiles.