Bruce Roe, Skype interview by Kathryn Maxson, conducted from Durham, NC, 30 March 2012. After a sabbatical in Frederick Sanger’s laboratory in Cambridge, UK, Bruce Roe became Professor of Chemistry and Biochemistry at the University of Oklahoma. He directed the genome center at the University of Oklahoma, founded in 1990, for the duration of the HGP. This center is now the Advanced Center for Genome Technology (ACGT). Roe’s long career in science has spawned significant progress in the development and implementation of large-scale DNA sequencing technologies. Many scientists currently at the forefront of genomics have trained in his laboratory. Roe was and is a strong supporter of the Bermuda Principles. This transcript is available beginning 1 July 2014. Keywords: Human Genome Project, HGP, interview, Bermuda Principles, Bermuda Accord, International Strategy Meetings on Human Genome Sequencing, data sharing, science policy, genomics, genome, genome sequence, genetics, DNA sequence, DNA, deoxyribonucleic acid, NIH, National Institutes of Health, DOE, Department of Energy, University of Oklahoma, Advanced Center for Genome Technology, ACGT, Bruce Roe.