Investigating Exposure to Perfluoroalkyl Substances (PFASs) in Indoor Environments

Perfluoroalkyl substances (PFASs) are a class of chemicals used as stain and water repellents in consumer products and are prevalent in human tissues. However, they are also associated with adverse health effects and exposure pathways are not well understood. We recruited a cohort of 40 adults to determine if specific exposure pathways (inhalation, dermal absorption or dust exposure) or personal behaviors were predictive of serum levels. We detected six PFAS metabolite compounds in serum, as well as a range of precursor molecules in hand wipes, silicone wristbands, and dust. A number of personal behaviors were significantly associated with serum levels, including hand washing, water filtration, vacuuming, and microwavable food intake. Overall, our data suggest that certain cleaning behaviors can modulate exposure to PFASs, and that hand washing may be an effective way to minimize exposure.