Pre-Pregnancy Weight and Symptoms of Attention Deficit Hyperactivity Disorder and Executive Functioning Behaviors in Preschool Children.

Fuemmeler, Bernard F

Zucker, Nancy

Sheng, Yaou

Sanchez, Carmen E

Maguire, Rachel

Murphy, Susan K

Kollins, Scott H

Hoyo, Cathrine

2019-04-01T14:58:19Z

2019-04-01T14:58:19Z

2019-02-25

2019-04-01T14:58:18Z

This study examines pre-pregnancy Body Mass Index (BMI) and gestational weight gain (GWG) in relation to early childhood Attention Deficit Hyperactivity Disorder (ADHD) symptoms and related executive self-regulation behaviors. The analyses sample (n = 331) included a subsample of participants from a birth cohort recruited from prenatal clinics and hospital facilities from April 2005 to June 2011 in Durham, North Carolina. Pre-pregnancy BMI was calculated from weight at the last menstrual period and height was extracted from medical records. Gestational weight gain was calculated from pre-pregnancy weight and weight measured at the time of delivery. ADHD symptoms and executive self-regulation behaviors were assessed by maternal report (mean age = 3 years). Multivariable regression methods with inverse probability weighting (IPW) were used to evaluate associations accounting for sample selection bias and confounding. Pre-pregnancy BMI at levels ≥35 was positively associated with higher ADHD symptoms and worse executive self-regulation behaviors (inhibitory control and attention). Compared to adequate GWG, less than adequate GWG was related to more ADHD hyperactive-impulsive symptoms, whereas greater than adequate GWG was related to more problematic behaviors related to working memory and planning. The findings support a link between maternal weight and child neurodevelopment. Continued research that help identify biological mechanisms are needed.

ijerph16040667

1661-7827

1660-4601

https://hdl.handle.net/10161/18196

eng

MDPI AG

International journal of environmental research and public health

10.3390/ijerph16040667

ADHD

child development

gestational weight gain

maternal obesity

pregnancy

Pre-Pregnancy Weight and Symptoms of Attention Deficit Hyperactivity Disorder and Executive Functioning Behaviors in Preschool Children.

Journal article

Zucker, Nancy|0000-0003-2278-5008

Murphy, Susan K|0000-0001-8298-7272

Kollins, Scott H|0000-0001-6847-6935

667

667

4

School of Medicine

Duke

Psychology and Neuroscience

Trinity College of Arts & Sciences

Center for Child and Family Policy

Sanford School of Public Policy

Duke Cancer Institute

Institutes and Centers

Duke Clinical Research Institute

Duke Institute for Brain Sciences

University Institutes and Centers

Institutes and Provost's Academic Units

Psychiatry & Behavioral Sciences, Addictions

Psychiatry & Behavioral Sciences

Clinical Science Departments

Environmental Sciences and Policy

Nicholas School of the Environment

Pathology

Published

16