Risk of coronary artery disease in patients with ankylosing spondylitis: a systematic review and meta-analysis.
| dc.contributor.author | Ungprasert, Patompong | |
| dc.contributor.author | Srivali, Narat | |
| dc.contributor.author | Kittanamongkolchai, Wonngarm | |
| dc.date.accessioned | 2023-11-23T12:31:09Z | |
| dc.date.available | 2023-11-23T12:31:09Z | |
| dc.date.issued | 2015-03 | |
| dc.date.updated | 2023-11-23T12:31:08Z | |
| dc.description.abstract | ObjectiveTo investigate the association between coronary artery disease (CAD) and ankylosing spondylitis (AS).MethodsWe conducted a systematic review and meta-analysis of observational studies that reported relative risks, hazard ratios, standardized prevalence ratio or standardized incidence ratios with 95% confidence comparing CAD risk in patients with AS versus non-AS controls. Pooled risk ratios and 95% confidence intervals (CIs) were calculated using a random-effect, generic inverse variance of DerSimonian and Laird.ResultsOut of 229 potentially relevant articles, ten studies (five retrospective cohort studies and five cross-sectional studies) were identified and included in our data analysis. The overall pooled risk ratio of CAD in patients with AS was 1.41 (95% CI: 1.29-1.54). The pooled risk ratios for cross-sectional and cohort studies were 2.08 (95% CI: 1.28-3.40) and 1.36 (95% CI: 1.31-1.41), respectively. The statistical heterogeneity of this meta-analysis was moderate with an I(2) of 56%.ConclusionsOur study demonstrated a statistically significant increased CAD risk among patients with AS with 41% excess risk. | |
| dc.identifier | atm-03-04-51 | |
| dc.identifier.issn | 2305-5839 | |
| dc.identifier.issn | 2305-5847 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.relation.ispartof | Annals of translational medicine | |
| dc.relation.isversionof | 10.3978/j.issn.2305-5839.2015.02.05 | |
| dc.subject | Meta-analysis | |
| dc.subject | ankylosing spondylitis (AS) | |
| dc.subject | epidemiology | |
| dc.subject | venous thromboembolism | |
| dc.title | Risk of coronary artery disease in patients with ankylosing spondylitis: a systematic review and meta-analysis. | |
| dc.type | Journal article | |
| duke.contributor.orcid | Srivali, Narat|0000-0002-6945-329X | |
| pubs.begin-page | 51 | |
| pubs.issue | 4 | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | Clinical Science Departments | |
| pubs.organisational-group | Medicine | |
| pubs.organisational-group | Medicine, Pulmonary, Allergy, and Critical Care Medicine | |
| pubs.publication-status | Published | |
| pubs.volume | 3 |
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