The enduring importance of family health history in the era of genomic medicine and risk assessment.

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2020-04-22

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Abstract

Improving disease risk prediction and tailoring preventive interventions to patient risk factors is one of the primary goals of precision medicine. Family health history is the traditional approach to quickly gather genetic and environmental data relevant to the patient. While the utility of family health history is well-documented, its utilization is variable, in part due to lack of patient and provider knowledge and incomplete or inaccurate data. With the advances and reduced costs of sequencing technologies, comprehensive sequencing tests can be performed as a risk assessment tool. We provide an overview of each of these risk assessment approaches, the benefits and limitations and implementation challenges.

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Published Version (Please cite this version)

10.2217/pme-2019-0091

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Haga, Susanne B, and Lori A Orlando (2020). The enduring importance of family health history in the era of genomic medicine and risk assessment. Per Med. 10.2217/pme-2019-0091 Retrieved from https://hdl.handle.net/10161/20584.

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Haga

Susanne B Haga

Professor in Medicine

My research interests focus on issues affecting the translation of genomics to clinical practice. Specifically, I have a strong interest in education, with each of my research projects involving some component of professional, public or patient education, including development of educational materials about genomic research in general, pharmacogenetic testing, and communicating genetic test results, in addition to undergraduate teaching in genetics/genomics, ethics, and policy.

Areas of expertise: Bioethics and Health Behavior


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