Geographic information system-based screening for TB, HIV, and syphilis (GIS-THIS): a cross-sectional study.
dc.contributor.author | Goswami, Neela D | |
dc.contributor.author | Hecker, Emily J | |
dc.contributor.author | Vickery, Carter | |
dc.contributor.author | Ahearn, Marshall A | |
dc.contributor.author | Cox, Gary M | |
dc.contributor.author | Holland, David P | |
dc.contributor.author | Naggie, Susanna | |
dc.contributor.author | Piedrahita, Carla | |
dc.contributor.author | Mosher, Ann | |
dc.contributor.author | Torres, Yvonne | |
dc.contributor.author | Norton, Brianna L | |
dc.contributor.author | Suchindran, Sujit | |
dc.contributor.author | Park, Paul H | |
dc.contributor.author | Turner, Debbie | |
dc.contributor.author | Stout, Jason E | |
dc.contributor.editor | Pai, Madhukar | |
dc.coverage.spatial | United States | |
dc.date.accessioned | 2017-04-01T13:22:03Z | |
dc.date.available | 2017-04-01T13:22:03Z | |
dc.date.issued | 2012 | |
dc.description.abstract | OBJECTIVE: To determine the feasibility and case detection rate of a geographic information systems (GIS)-based integrated community screening strategy for tuberculosis, syphilis, and human immunodeficiency virus (HIV). DESIGN: Prospective cross-sectional study of all participants presenting to geographic hot spot screenings in Wake County, North Carolina. METHODS: The residences of tuberculosis, HIV, and syphilis cases incident between 1/1/05-12/31/07 were mapped. Areas with high densities of all 3 diseases were designated "hot spots." Combined screening for tuberculosis, HIV, and syphilis were conducted at the hot spots; participants with positive tests were referred to the health department. RESULTS AND CONCLUSIONS: Participants (N = 247) reported high-risk characteristics: 67% previously incarcerated, 40% had lived in a homeless shelter, and 29% had a history of crack cocaine use. However, 34% reported never having been tested for HIV, and 41% did not recall prior tuberculin skin testing. Screening identified 3% (8/240) of participants with HIV infection, 1% (3/239) with untreated syphilis, and 15% (36/234) with latent tuberculosis infection. Of the eight persons with HIV, one was newly diagnosed and co-infected with latent tuberculosis; he was treated for latent TB and linked to an HIV provider. Two other HIV-positive persons had fallen out of care, and as a result of the study were linked back into HIV clinics. Of 27 persons with latent tuberculosis offered therapy, nine initiated and three completed treatment. GIS-based screening can effectively penetrate populations with high disease burden and poor healthcare access. Linkage to care remains challenging and will require creative interventions to impact morbidity. | |
dc.identifier | ||
dc.identifier | PONE-D-12-14146 | |
dc.identifier.eissn | 1932-6203 | |
dc.identifier.uri | ||
dc.language | eng | |
dc.publisher | Public Library of Science (PLoS) | |
dc.relation.ispartof | PLoS One | |
dc.relation.isversionof | 10.1371/journal.pone.0046029 | |
dc.subject | Adult | |
dc.subject | Cross-Sectional Studies | |
dc.subject | Feasibility Studies | |
dc.subject | Female | |
dc.subject | Follow-Up Studies | |
dc.subject | Geographic Information Systems | |
dc.subject | Geography | |
dc.subject | HIV Infections | |
dc.subject | Humans | |
dc.subject | Incidence | |
dc.subject | Male | |
dc.subject | Mass Screening | |
dc.subject | Middle Aged | |
dc.subject | North Carolina | |
dc.subject | Prospective Studies | |
dc.subject | Syphilis | |
dc.subject | Tuberculosis | |
dc.subject | Young Adult | |
dc.title | Geographic information system-based screening for TB, HIV, and syphilis (GIS-THIS): a cross-sectional study. | |
dc.type | Journal article | |
duke.contributor.orcid | Naggie, Susanna|0000-0001-7721-6975 | |
duke.contributor.orcid | Stout, Jason E|0000-0002-6698-8176 | |
pubs.author-url | ||
pubs.begin-page | e46029 | |
pubs.issue | 10 | |
pubs.organisational-group | Basic Science Departments | |
pubs.organisational-group | Clinical Science Departments | |
pubs.organisational-group | Duke | |
pubs.organisational-group | Duke Clinical Research Institute | |
pubs.organisational-group | Faculty | |
pubs.organisational-group | Institutes and Centers | |
pubs.organisational-group | Medicine | |
pubs.organisational-group | Medicine, Infectious Diseases | |
pubs.organisational-group | Molecular Genetics and Microbiology | |
pubs.organisational-group | School of Medicine | |
pubs.publication-status | Published | |
pubs.volume | 7 |
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