Geographic information system-based screening for TB, HIV, and syphilis (GIS-THIS): a cross-sectional study.

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Goswami, Neela D

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Hecker, Emily J

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Vickery, Carter

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Ahearn, Marshall A

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Cox, Gary M

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Holland, David P

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Naggie, Susanna

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Piedrahita, Carla

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Mosher, Ann

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Torres, Yvonne

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Norton, Brianna L

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Suchindran, Sujit

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Park, Paul H

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Turner, Debbie

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Stout, Jason E

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Pai, Madhukar

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United States

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2017-04-01T13:22:03Z

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2017-04-01T13:22:03Z

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2012

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OBJECTIVE: To determine the feasibility and case detection rate of a geographic information systems (GIS)-based integrated community screening strategy for tuberculosis, syphilis, and human immunodeficiency virus (HIV). DESIGN: Prospective cross-sectional study of all participants presenting to geographic hot spot screenings in Wake County, North Carolina. METHODS: The residences of tuberculosis, HIV, and syphilis cases incident between 1/1/05-12/31/07 were mapped. Areas with high densities of all 3 diseases were designated "hot spots." Combined screening for tuberculosis, HIV, and syphilis were conducted at the hot spots; participants with positive tests were referred to the health department. RESULTS AND CONCLUSIONS: Participants (N = 247) reported high-risk characteristics: 67% previously incarcerated, 40% had lived in a homeless shelter, and 29% had a history of crack cocaine use. However, 34% reported never having been tested for HIV, and 41% did not recall prior tuberculin skin testing. Screening identified 3% (8/240) of participants with HIV infection, 1% (3/239) with untreated syphilis, and 15% (36/234) with latent tuberculosis infection. Of the eight persons with HIV, one was newly diagnosed and co-infected with latent tuberculosis; he was treated for latent TB and linked to an HIV provider. Two other HIV-positive persons had fallen out of care, and as a result of the study were linked back into HIV clinics. Of 27 persons with latent tuberculosis offered therapy, nine initiated and three completed treatment. GIS-based screening can effectively penetrate populations with high disease burden and poor healthcare access. Linkage to care remains challenging and will require creative interventions to impact morbidity.

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https://www.ncbi.nlm.nih.gov/pubmed/23056227

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PONE-D-12-14146

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1932-6203

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https://hdl.handle.net/10161/13902

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eng

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Public Library of Science (PLoS)

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PLoS One

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10.1371/journal.pone.0046029

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Adult

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Cross-Sectional Studies

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Feasibility Studies

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Female

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Follow-Up Studies

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Geographic Information Systems

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Geography

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HIV Infections

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Humans

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Incidence

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Male

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Mass Screening

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Middle Aged

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North Carolina

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Prospective Studies

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Syphilis

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Tuberculosis

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Young Adult

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Geographic information system-based screening for TB, HIV, and syphilis (GIS-THIS): a cross-sectional study.

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Journal article

duke.contributor.orcid

Naggie, Susanna|0000-0001-7721-6975

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Stout, Jason E|0000-0002-6698-8176

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https://www.ncbi.nlm.nih.gov/pubmed/23056227

pubs.begin-page

e46029

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10

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Basic Science Departments

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Clinical Science Departments

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Duke

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Duke Clinical Research Institute

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Faculty

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Institutes and Centers

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Medicine

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Medicine, Infectious Diseases

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Molecular Genetics and Microbiology

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School of Medicine

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Published

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7

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