Measuring morphological features using light-scattering spectroscopy and Fourier-domain low-coherence interferometry.

dc.contributor.author

Robles, Francisco E

dc.contributor.author

Wax, Adam

dc.coverage.spatial

United States

dc.date.accessioned

2011-06-21T17:27:42Z

dc.date.issued

2010-02-01

dc.description.abstract

We present measurements of morphological features in a thick turbid sample using light-scattering spectroscopy (LSS) and Fourier-domain low-coherence interferometry (fLCI) by processing with the dual-window (DW) method. A parallel frequency domain optical coherence tomography (OCT) system with a white-light source is used to image a two-layer phantom containing polystyrene beads of diameters 4.00 and 6.98 mum on the top and bottom layers, respectively. The DW method decomposes each OCT A-scan into a time-frequency distribution with simultaneously high spectral and spatial resolution. The spectral information from localized regions in the sample is used to determine scatterer structure. The results show that the two scatterer populations can be differentiated using LSS and fLCI.

dc.description.version

Version of Record

dc.identifier

http://www.ncbi.nlm.nih.gov/pubmed/20125721

dc.identifier

195211

dc.identifier.eissn

1539-4794

dc.identifier.uri

https://hdl.handle.net/10161/4226

dc.language

eng

dc.language.iso

en_US

dc.publisher

The Optical Society

dc.relation.ispartof

Opt Lett

dc.relation.journal

Optics Letters

dc.subject

Aluminum Oxide

dc.subject

Ethylene Glycol

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Fourier Analysis

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Interferometry

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Light

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Models, Statistical

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Nanoparticles

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Nanotechnology

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Scattering, Radiation

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Spectrophotometry

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Surface Plasmon Resonance

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Water

dc.title

Measuring morphological features using light-scattering spectroscopy and Fourier-domain low-coherence interferometry.

dc.title.alternative
dc.type

Journal article

duke.date.pubdate

2010-2-1

duke.description.issue

3

duke.description.volume

35

pubs.author-url

http://www.ncbi.nlm.nih.gov/pubmed/20125721

pubs.begin-page

360

pubs.end-page

362

pubs.issue

3

pubs.organisational-group

Biomedical Engineering

pubs.organisational-group

Duke

pubs.organisational-group

Duke Institute for Brain Sciences

pubs.organisational-group

Institutes and Provost's Academic Units

pubs.organisational-group

Pratt School of Engineering

pubs.organisational-group

University Institutes and Centers

pubs.publication-status

Published

pubs.volume

35

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