A randomized controlled trial to evaluate the effectiveness of CouPLES: a spouse-assisted lifestyle change intervention to improve low-density lipoprotein cholesterol.
dc.contributor.author | Voils, Corrine I | |
dc.contributor.author | Coffman, Cynthia J | |
dc.contributor.author | Yancy, William S | |
dc.contributor.author | Weinberger, Morris | |
dc.contributor.author | Jeffreys, Amy S | |
dc.contributor.author | Datta, Santanu | |
dc.contributor.author | Kovac, Stacey | |
dc.contributor.author | McKenzie, Jamiyla | |
dc.contributor.author | Smith, Rose | |
dc.contributor.author | Bosworth, Hayden B | |
dc.date.accessioned | 2024-02-01T16:41:41Z | |
dc.date.available | 2024-02-01T16:41:41Z | |
dc.date.issued | 2013-01 | |
dc.description.abstract | ObjectiveThis randomized controlled trial evaluated the effectiveness of a telephone-delivered, spouse-assisted lifestyle intervention to reduce patient LDL-C.MethodFrom 2007 to 2010, 255 outpatients with LDL-C>76 mg/dL and their spouses from the Durham Veterans Affairs Medical Center were randomized to intervention or usual care. The intervention comprised nine monthly goal-setting telephone calls to patients and support planning calls to spouses. Outcomes were assessed at 11 months.ResultsPatients were 95% male and 65% White. LDL-C did not differ between groups (mean difference = 2.3 mg/dL, 95% CI = -3.6, 8.3, p = 0.44), nor did the odds of meeting goal LDL-C (OR = 0.95, 95% CI = 0.6, 1.7; p = 0.87). Intakes of calories (p = 0.03), total fat (p = 0.02), and saturated fat (p = 0.02) were lower for the intervention group. Cholesterol and fiber intake did not differ between groups (p = 0.11 and 0.26, respectively). The estimated rate of moderate intensity physical activity per week was 20% higher in the intervention group (IRR = 1.2, 95% CI = 1.0, 1.5, p = 0.06). Most participants did not experience a change in cholesterol medication usage during the study period in the intervention (71.7%) and usual care (78.9%) groups.ConclusionThis intervention might be an adjunct to usual primary care to improve adherence to lifestyle behaviors. | |
dc.identifier | S0091-7435(12)00555-5 | |
dc.identifier.issn | 0091-7435 | |
dc.identifier.issn | 1096-0260 | |
dc.identifier.uri | ||
dc.language | eng | |
dc.publisher | Elsevier BV | |
dc.relation.ispartof | Preventive medicine | |
dc.relation.isversionof | 10.1016/j.ypmed.2012.11.001 | |
dc.rights.uri | ||
dc.subject | Humans | |
dc.subject | Confidence Intervals | |
dc.subject | Odds Ratio | |
dc.subject | Risk Reduction Behavior | |
dc.subject | Spouses | |
dc.subject | Social Support | |
dc.subject | Aged | |
dc.subject | Middle Aged | |
dc.subject | Health Services | |
dc.subject | North Carolina | |
dc.subject | Female | |
dc.subject | Male | |
dc.subject | Hypobetalipoproteinemias | |
dc.subject | Power, Psychological | |
dc.title | A randomized controlled trial to evaluate the effectiveness of CouPLES: a spouse-assisted lifestyle change intervention to improve low-density lipoprotein cholesterol. | |
dc.type | Journal article | |
duke.contributor.orcid | Coffman, Cynthia J|0000-0002-4554-1463 | |
duke.contributor.orcid | Bosworth, Hayden B|0000-0001-6188-9825 | |
pubs.begin-page | 46 | |
pubs.end-page | 52 | |
pubs.issue | 1 | |
pubs.organisational-group | Duke | |
pubs.organisational-group | School of Medicine | |
pubs.organisational-group | Faculty | |
pubs.organisational-group | Basic Science Departments | |
pubs.organisational-group | Clinical Science Departments | |
pubs.organisational-group | Institutes and Centers | |
pubs.organisational-group | Biostatistics & Bioinformatics | |
pubs.organisational-group | Medicine | |
pubs.organisational-group | Psychiatry & Behavioral Sciences | |
pubs.organisational-group | Medicine, General Internal Medicine | |
pubs.organisational-group | Duke Cancer Institute | |
pubs.organisational-group | Duke Clinical Research Institute | |
pubs.organisational-group | Institutes and Provost's Academic Units | |
pubs.organisational-group | Center for the Study of Aging and Human Development | |
pubs.organisational-group | Initiatives | |
pubs.organisational-group | Duke Science & Society | |
pubs.organisational-group | Population Health Sciences | |
pubs.organisational-group | Duke Innovation & Entrepreneurship | |
pubs.organisational-group | Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences | |
pubs.organisational-group | Psychiatry & Behavioral Sciences, Adult Psychiatry & Psychology | |
pubs.organisational-group | Duke - Margolis Center For Health Policy | |
pubs.organisational-group | Biostatistics & Bioinformatics, Division of Biostatistics | |
pubs.publication-status | Published | |
pubs.volume | 56 |
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