A randomized controlled trial to evaluate the effectiveness of CouPLES: a spouse-assisted lifestyle change intervention to improve low-density lipoprotein cholesterol.

dc.contributor.author

Voils, Corrine I

dc.contributor.author

Coffman, Cynthia J

dc.contributor.author

Yancy, William S

dc.contributor.author

Weinberger, Morris

dc.contributor.author

Jeffreys, Amy S

dc.contributor.author

Datta, Santanu

dc.contributor.author

Kovac, Stacey

dc.contributor.author

McKenzie, Jamiyla

dc.contributor.author

Smith, Rose

dc.contributor.author

Bosworth, Hayden B

dc.date.accessioned

2024-02-01T16:41:41Z

dc.date.available

2024-02-01T16:41:41Z

dc.date.issued

2013-01

dc.description.abstract

Objective

This randomized controlled trial evaluated the effectiveness of a telephone-delivered, spouse-assisted lifestyle intervention to reduce patient LDL-C.

Method

From 2007 to 2010, 255 outpatients with LDL-C>76 mg/dL and their spouses from the Durham Veterans Affairs Medical Center were randomized to intervention or usual care. The intervention comprised nine monthly goal-setting telephone calls to patients and support planning calls to spouses. Outcomes were assessed at 11 months.

Results

Patients were 95% male and 65% White. LDL-C did not differ between groups (mean difference = 2.3 mg/dL, 95% CI = -3.6, 8.3, p = 0.44), nor did the odds of meeting goal LDL-C (OR = 0.95, 95% CI = 0.6, 1.7; p = 0.87). Intakes of calories (p = 0.03), total fat (p = 0.02), and saturated fat (p = 0.02) were lower for the intervention group. Cholesterol and fiber intake did not differ between groups (p = 0.11 and 0.26, respectively). The estimated rate of moderate intensity physical activity per week was 20% higher in the intervention group (IRR = 1.2, 95% CI = 1.0, 1.5, p = 0.06). Most participants did not experience a change in cholesterol medication usage during the study period in the intervention (71.7%) and usual care (78.9%) groups.

Conclusion

This intervention might be an adjunct to usual primary care to improve adherence to lifestyle behaviors.
dc.identifier

S0091-7435(12)00555-5

dc.identifier.issn

0091-7435

dc.identifier.issn

1096-0260

dc.identifier.uri

https://hdl.handle.net/10161/30045

dc.language

eng

dc.publisher

Elsevier BV

dc.relation.ispartof

Preventive medicine

dc.relation.isversionof

10.1016/j.ypmed.2012.11.001

dc.rights.uri

https://creativecommons.org/licenses/by-nc/4.0

dc.subject

Humans

dc.subject

Confidence Intervals

dc.subject

Odds Ratio

dc.subject

Risk Reduction Behavior

dc.subject

Spouses

dc.subject

Social Support

dc.subject

Aged

dc.subject

Middle Aged

dc.subject

Health Services

dc.subject

North Carolina

dc.subject

Female

dc.subject

Male

dc.subject

Hypobetalipoproteinemias

dc.subject

Power, Psychological

dc.title

A randomized controlled trial to evaluate the effectiveness of CouPLES: a spouse-assisted lifestyle change intervention to improve low-density lipoprotein cholesterol.

dc.type

Journal article

duke.contributor.orcid

Coffman, Cynthia J|0000-0002-4554-1463

duke.contributor.orcid

Bosworth, Hayden B|0000-0001-6188-9825

pubs.begin-page

46

pubs.end-page

52

pubs.issue

1

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

pubs.organisational-group

Faculty

pubs.organisational-group

Basic Science Departments

pubs.organisational-group

Clinical Science Departments

pubs.organisational-group

Institutes and Centers

pubs.organisational-group

Biostatistics & Bioinformatics

pubs.organisational-group

Medicine

pubs.organisational-group

Psychiatry & Behavioral Sciences

pubs.organisational-group

Medicine, General Internal Medicine

pubs.organisational-group

Duke Cancer Institute

pubs.organisational-group

Duke Clinical Research Institute

pubs.organisational-group

Institutes and Provost's Academic Units

pubs.organisational-group

Center for the Study of Aging and Human Development

pubs.organisational-group

Initiatives

pubs.organisational-group

Duke Science & Society

pubs.organisational-group

Population Health Sciences

pubs.organisational-group

Duke Innovation & Entrepreneurship

pubs.organisational-group

Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences

pubs.organisational-group

Psychiatry & Behavioral Sciences, Adult Psychiatry & Psychology

pubs.organisational-group

Duke - Margolis Center For Health Policy

pubs.organisational-group

Biostatistics & Bioinformatics, Division of Biostatistics

pubs.publication-status

Published

pubs.volume

56

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
1-s2.0-S0091743512005555-main.pdf
Size:
386.47 KB
Format:
Adobe Portable Document Format