High-Flow Nasal Cannula versus Continuous Positive Airway Pressure in Critical Bronchiolitis: A Randomized Controlled Pilot
dc.contributor.author | Cesar, Regina Grigolli | |
dc.contributor.author | Bispo, Bibiane Ramos Pinheiro | |
dc.contributor.author | Felix, Priscilla Helena Costa Alves | |
dc.contributor.author | Modolo, Maria Carolina Caparica | |
dc.contributor.author | Souza, Andreia Aparecida Freitas | |
dc.contributor.author | Horigoshi, Nelson K | |
dc.contributor.author | Rotta, Alexandre T | |
dc.date.accessioned | 2020-05-01T13:24:13Z | |
dc.date.available | 2020-05-01T13:24:13Z | |
dc.date.updated | 2020-05-01T13:24:13Z | |
dc.description.abstract | <jats:title>Abstract</jats:title><jats:p>We conducted a randomized controlled pilot study in infants with critical bronchiolitis (n = 63) comparing high-flow nasal cannula (HFNC, n = 35) to continuous positive airway pressure (CPAP, n = 28). The primary outcome was treatment failure, defined as the need for bilevel positive pressure ventilation or endotracheal intubation. Treatment failure occurred in 10 patients (35.7%) in the CPAP group and 13 patients (37.1%) in the HFNC group (p = 0.88). Pediatric intensive care unit length of stay was similar between the CPAP and HFNC groups (5 [4–7] days and 5 [4–8] days, p = 0.46, respectively). In this pilot study, treatment with HFNC resulted in a rate of treatment failure similar to CPAP.</jats:p> | |
dc.identifier.issn | 2146-4618 | |
dc.identifier.issn | 2146-4626 | |
dc.identifier.uri | ||
dc.language | en | |
dc.publisher | Georg Thieme Verlag KG | |
dc.relation.ispartof | Journal of Pediatric Intensive Care | |
dc.relation.isversionof | 10.1055/s-0040-1709656 | |
dc.title | High-Flow Nasal Cannula versus Continuous Positive Airway Pressure in Critical Bronchiolitis: A Randomized Controlled Pilot | |
dc.type | Journal article | |
duke.contributor.orcid | Rotta, Alexandre T|0000-0002-4406-2276 | |
pubs.organisational-group | School of Medicine | |
pubs.organisational-group | Pediatrics, Critical Care Medicine | |
pubs.organisational-group | Duke | |
pubs.organisational-group | Pediatrics | |
pubs.organisational-group | Clinical Science Departments | |
pubs.publication-status | Published online |