Awake Spinal Fusion Is Associated with Reduced Length of Stay, Opioid Use, and Time to Ambulation Compared to General Anesthesia: A Matched Cohort Study.

dc.contributor.author

Sykes, David AW

dc.contributor.author

Tabarestani, Troy Q

dc.contributor.author

Chaudhry, Nauman S

dc.contributor.author

Salven, David S

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Shaffrey, Christopher I

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Bullock, W Michael

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Guinn, Nicole R

dc.contributor.author

Gadsden, Jeffrey

dc.contributor.author

Berger, Miles

dc.contributor.author

Abd-El-Barr, Muhammad M

dc.date.accessioned

2023-06-12T20:46:58Z

dc.date.available

2023-06-12T20:46:58Z

dc.date.issued

2023-05

dc.date.updated

2023-06-12T20:46:57Z

dc.description.abstract

Objective

There is increasing interest in awake spinal fusion under spinal anesthesia (SA). Evidence supporting SA has been positive, albeit limited. The authors set out to investigate the effects of SA vs general anesthesia (GA) for spinal fusion procedures on length of stay (LOS), opioid use, time to ambulation (TTA), and procedure duration.

Methods

The authors performed a retrospective review of a single surgeon's patients who underwent lumbar fusions under SA vs GA from June of 2020 to June of 2022. SA patients were compared to demographically matched GA counterparts undergoing comparable procedures. Analyzed outcomes include operative time, opioid usage in morphine milligram equivalents (MME), TTA, and LOS.

Results

10 SA patients were matched to 10 GA counterparts. The cohort had a mean age of 66.77, a mean body mass index of 27.73 kg/m2, and a median American Society of Anesthesiologists Physical Status Score of 3.00. LOS was lower in SA vs GA patients (12.87 vs 50.79 hours, p=0.001). Opioid utilization was reduced in SA vs GA patients (10.76 vs 31.43 MME, p=0.006). TTA was reduced in SA vs GA patients (7.22 vs 29.87 hours, p=0.022). Procedure duration was not significantly reduced in SA patients compared to GA patients (139.3 vs 188.2 minutes, p=0.089).

Conclusion

These preliminary retrospective results suggest the use of SA rather than GA for lumbar fusions is associated with reduced hospital LOS, reduced opioid utilization, and reduced TTA. Future randomized prospective studies are warranted to determine if SA usage truly leads to these beneficial outcomes.
dc.identifier

S1878-8750(23)00613-7

dc.identifier.issn

1878-8750

dc.identifier.issn

1878-8769

dc.identifier.uri

https://hdl.handle.net/10161/27922

dc.language

eng

dc.publisher

Elsevier BV

dc.relation.ispartof

World neurosurgery

dc.relation.isversionof

10.1016/j.wneu.2023.05.001

dc.subject

Length of Stay

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Lumbar Fusion

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Opioids

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Spinal Anesthesia

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Spine Surgery

dc.title

Awake Spinal Fusion Is Associated with Reduced Length of Stay, Opioid Use, and Time to Ambulation Compared to General Anesthesia: A Matched Cohort Study.

dc.type

Journal article

duke.contributor.orcid

Shaffrey, Christopher I|0000-0001-9760-8386

duke.contributor.orcid

Bullock, W Michael|0000-0002-8088-8390

duke.contributor.orcid

Guinn, Nicole R|0000-0001-6073-6317

duke.contributor.orcid

Gadsden, Jeffrey|0000-0003-3971-3879

duke.contributor.orcid

Berger, Miles|0000-0002-2386-5061

duke.contributor.orcid

Abd-El-Barr, Muhammad M|0000-0001-7151-2861

pubs.begin-page

S1878-8750(23)00613-7

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

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Student

pubs.organisational-group

Clinical Science Departments

pubs.organisational-group

Anesthesiology

pubs.organisational-group

Anesthesiology, Regional

pubs.organisational-group

Orthopaedic Surgery

pubs.organisational-group

Neurosurgery

pubs.publication-status

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