Cell Saver for Adult Spinal Deformity Surgery Reduces Cost.

dc.contributor.author

Gum, Jeffrey L

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Carreon, Leah Yacat

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Kelly, Michael P

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Hostin, Richard

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Robinson, Chessie

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Burton, Douglas C

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Polly, David W

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Shaffrey, Christopher I

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LaFage, Virginie

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Schwab, Frank J

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Ames, Christopher P

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Kim, Han Jo

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Smith, Justin S

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Bess, R Shay

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International Spine Study Group

dc.date.accessioned

2023-07-09T21:23:58Z

dc.date.available

2023-07-09T21:23:58Z

dc.date.issued

2017-07

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2023-07-09T21:23:56Z

dc.description.abstract

Study design

Retrospective cohort.

Objectives

To determine if the use of cell saver reduces overall blood costs in adult spinal deformity (ASD) surgery.

Summary of background data

Recent studies have questioned the clinical value of cell saver during spine procedures.

Methods

ASD patients enrolled in a prospective, multicenter surgical database who had complete preoperative and surgical data were identified. Patients were stratified into (1) cell saver available during surgery, but no intraoperative autologous infusion (No Infusion group), or (2) cell saver available and received autologous infusion (Infusion group).

Results

There were 427 patients in the Infusion group and 153 in the No infusion group. Patients in both groups had similar demographics. Mean autologous infusion volume was 698 mL. The Infusion group had a higher percentage of EBL relative to the estimated blood volume (42.2%) than the No Infusion group (19.6%, p < .000). Allogeneic transfusion was more common in the Infusion group (255/427, 60%) than the No Infusion group (67/153, 44%, p = .001). The number of allogeneic blood units transfused was also higher in the Infusion group (2.4) than the No Infusion group (1.7, p = .009). Total blood costs ranged from $396 to $2,146 in the No Infusion group and from $1,262 to $5,088 in the Infusion group. If the cost of cell saver blood was transformed into costs of allogeneic blood, total blood costs for the Infusion group would range from $840 to $5,418. Thus, cell saver use yielded a mean cost savings ranging from $330 to $422 (allogeneic blood averted). Linear regression showed that after an EBL of 614 mL, cell saver becomes cost-efficient.

Conclusion

Compared to transfusing allogeneic blood, cell saver autologous infusion did not reduce the proportion or the volume of allogeneic transfusion for patients undergoing surgery for adult spinal deformity. The use of cell saver becomes cost-efficient above an EBL of 614 mL, producing a cost savings of $330 to $422.

Level of evidence

Level III.
dc.identifier

S2212-134X(17)30019-9

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2212-134X

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2212-1358

dc.identifier.uri

https://hdl.handle.net/10161/28382

dc.language

eng

dc.publisher

Springer Science and Business Media LLC

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Spine deformity

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10.1016/j.jspd.2017.01.005

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International Spine Study Group

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Spine

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Humans

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Blood Loss, Surgical

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Postoperative Hemorrhage

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Blood Transfusion

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Blood Transfusion, Autologous

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Retrospective Studies

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Prospective Studies

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Aged

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Middle Aged

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Female

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Male

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Congenital Abnormalities

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Operative Blood Salvage

dc.title

Cell Saver for Adult Spinal Deformity Surgery Reduces Cost.

dc.type

Journal article

duke.contributor.orcid

Shaffrey, Christopher I|0000-0001-9760-8386

pubs.begin-page

272

pubs.end-page

276

pubs.issue

4

pubs.organisational-group

Duke

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School of Medicine

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Clinical Science Departments

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Orthopaedic Surgery

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Neurosurgery

pubs.publication-status

Published

pubs.volume

5

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