The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts.
Date
2011-12-28
Journal Title
Journal ISSN
Volume Title
Repository Usage Stats
views
downloads
Citation Stats
Attention Stats
Abstract
Cleft lip and/or palate (CL/P) increase mortality and morbidity risks for affected infants especially in less developed countries. This study aimed at assessing the effects of systematic pediatric care on neonatal mortality and hospitalizations of infants with cleft lip and/or palate (CL/P) in South America.The intervention group included live-born infants with isolated or associated CL/P in 47 hospitals between 2003 and 2005. The control group included live-born infants with CL/P between 2001 and 2002 in the same hospitals. The intervention group received systematic pediatric care between the 7th and 28th day of life. The primary outcomes were mortality between the 7th and 28th day of life and hospitalization days in this period among survivors adjusted for relevant baseline covariates.There were no significant mortality differences between the intervention and control groups. However, surviving infants with associated CL/P in the intervention group had fewer hospitalization days by about six days compared to the associated control group.Early systematic pediatric care may significantly reduce neonatal hospitalizations of infants with CL/P and additional birth defects in South America. Given the large healthcare and financial burden of CL/P on affected families and the relatively low cost of systematic pediatric care, improving access to such care may be a cost-effective public policy intervention.ClinicalTrials.gov: NCT00097149.
Type
Department
Description
Provenance
Subjects
Citation
Permalink
Published Version (Please cite this version)
Publication Info
Wehby, George L, Eduardo E Castilla, Norman Goco, Monica Rittler, Viviana Cosentino, Lorette Javois, Mark Kindem, Hrishikesh Chakraborty, et al. (2011). The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts. BMC pediatrics, 11(1). p. 121. 10.1186/1471-2431-11-121 Retrieved from https://hdl.handle.net/10161/21981.
This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.
Collections
Endorsement
Review
Supplemented By
Referenced By
Scholars@Duke
Hrishikesh Chakraborty
Hrishikesh Chakraborty, is a Professor in the Department of Biostatistics and Bioinformatics at Duke University and affiliated with the Duke Clinical Research Institute. He is an internationally experienced biostatistician whose work integrates statistical methodology, clinical trial design, data coordinating center leadership, and collaborative biomedical research. Over more than 25+ years of independent and collaborative research, he has contributed to more than 20+ clinical trials and authored more than 100 peer-reviewed publications. His research spans pragmatic and cluster-randomized trials, HIV/AIDS, maternal and child health, survival analysis, genomic medicine, dietary metabolomic biomarker discoveries, cardiovascular and kidney disease, pulmonary hypertension, pain management, and other areas of public health and clinical research.
Dr. Chakraborty has served as principal investigator for multiple data coordinating centers and has provided statistical leadership for large, multisite, federally funded research initiatives. His work encompasses the full research lifecycle, including study design, protocol development, sample-size and power calculations, data management and harmonization, study monitoring, statistical analysis, interpretation, and dissemination. His multidisciplinary background in statistics, biostatistics, and sociology supports a collaborative approach that connects rigorous quantitative methods with consequential clinical and public health questions.
Unless otherwise indicated, scholarly articles published by Duke faculty members are made available here with a CC-BY-NC (Creative Commons Attribution Non-Commercial) license, as enabled by the Duke Open Access Policy. If you wish to use the materials in ways not already permitted under CC-BY-NC, please consult the copyright owner. Other materials are made available here through the author’s grant of a non-exclusive license to make their work openly accessible.