The HO-1/CO System and Mitochondrial Quality Control in Skeletal Muscle.

dc.contributor.author	Gasier, Heath G
dc.contributor.author	Suliman, Hagir B
dc.contributor.author	Piantadosi, Claude A
dc.date.accessioned	2021-12-23T14:26:49Z
dc.date.available	2021-12-23T14:26:49Z
dc.date.issued	2021-10-22
dc.date.updated	2021-12-23T14:26:48Z
dc.description.abstract	Abstract Inducible heme oxygenase (HO)-1 catalyzes the breakdown of heme to biliverdin, iron and carbon monoxide (CO). CO binds to cytochrome c oxidase and alters mitochondrial redox balance and coordinately regulates mitochondrial quality control (MQC) during oxidant stress and inflammation. The hypothesis presented is that skeletal muscle HO-1/CO system helps modulate components in the MQC cycle during metabolic stress.
dc.identifier	00003677-900000000-99689
dc.identifier.issn	0091-6331
dc.identifier.issn	1538-3008
dc.identifier.uri	https://hdl.handle.net/10161/24126
dc.language	eng
dc.publisher	Ovid Technologies (Wolters Kluwer Health)
dc.relation.ispartof	Exercise and sport sciences reviews
dc.relation.isversionof	10.1249/jes.0000000000000277
dc.title	The HO-1/CO System and Mitochondrial Quality Control in Skeletal Muscle.
dc.type	Journal article
duke.contributor.orcid	Gasier, Heath G\|0000-0001-5895-4542
pubs.organisational-group	School of Medicine
pubs.organisational-group	Anesthesiology
pubs.organisational-group	Duke
pubs.organisational-group	Clinical Science Departments
pubs.organisational-group	Duke Cancer Institute
pubs.organisational-group	Institutes and Centers
pubs.publication-status	Published
pubs.volume	Publish Ahead of Print

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