Pulmonary blastomycosis presenting as primary lung cancer.
dc.contributor.author | Hussaini, Syed Mohammed Qasim | |
dc.contributor.author | Madut, Deng | |
dc.contributor.author | Tong, Betty C | |
dc.contributor.author | Pavlisko, Elizabeth N | |
dc.contributor.author | Schell, Wiley A | |
dc.contributor.author | Perfect, John R | |
dc.contributor.author | Thielman, Nathan M | |
dc.date.accessioned | 2019-06-21T17:45:28Z | |
dc.date.available | 2019-06-21T17:45:28Z | |
dc.date.issued | 2018-07-18 | |
dc.date.updated | 2019-06-21T17:45:26Z | |
dc.description.abstract | BACKGROUND:Blastomycosis is an endemic mycosis in North America that is caused by the dimorphic fungus Blastomyces dermatitidis. The illness is a systemic disease with a wide variety of pulmonary and extra-pulmonary manifestations. The initial presentation of blastomycosis may easily be mistaken for other infectious or non-infectious etiologies. CASE PRESENTATION:We present the case of a 52-year-old African-American male and former smoker that presented to his primary care provider with a 2-week history of non-productive cough, night sweats and weight loss. Initially diagnosed with primary lung malignancy, the patient was subsequently found to have pulmonary blastomycosis mimicking lung cancer. The patient underwent a successful course of treatment with posaconazole. CONCLUSIONS:Chronic blastomycosis can present with clinical and radiographic features indistinguishable from thoracic malignancies. There is no clinical syndrome specific for blastomycosis, thus a high degree of suspicion is required for early diagnosis. In this case report, we review recent evidence in radiographic features, diagnostic considerations and treatment of the disease. | |
dc.identifier | 10.1186/s12879-018-3244-0 | |
dc.identifier.issn | 1471-2334 | |
dc.identifier.issn | 1471-2334 | |
dc.identifier.uri | ||
dc.language | eng | |
dc.publisher | Springer Science and Business Media LLC | |
dc.relation.ispartof | BMC infectious diseases | |
dc.relation.isversionof | 10.1186/s12879-018-3244-0 | |
dc.subject | Lung | |
dc.subject | Humans | |
dc.subject | Blastomyces | |
dc.subject | Blastomycosis | |
dc.subject | Lung Neoplasms | |
dc.subject | Triazoles | |
dc.subject | DNA, Fungal | |
dc.subject | Antifungal Agents | |
dc.subject | Diagnosis, Differential | |
dc.subject | Tomography, X-Ray Computed | |
dc.subject | Middle Aged | |
dc.subject | Male | |
dc.subject | Positron Emission Tomography Computed Tomography | |
dc.title | Pulmonary blastomycosis presenting as primary lung cancer. | |
dc.type | Journal article | |
duke.contributor.orcid | Hussaini, Syed Mohammed Qasim|0000-0002-8006-5343 | |
duke.contributor.orcid | Madut, Deng|0000-0003-4023-3928 | |
duke.contributor.orcid | Tong, Betty C|0000-0002-3345-3124 | |
duke.contributor.orcid | Pavlisko, Elizabeth N|0000-0001-9598-3369 | |
duke.contributor.orcid | Perfect, John R|0000-0002-6606-9460|0000-0003-3465-5518 | |
duke.contributor.orcid | Thielman, Nathan M|0000-0001-8152-2879 | |
pubs.begin-page | 336 | |
pubs.issue | 1 | |
pubs.organisational-group | Staff | |
pubs.organisational-group | Duke | |
pubs.organisational-group | Medicine | |
pubs.organisational-group | Clinical Science Departments | |
pubs.organisational-group | School of Medicine | |
pubs.organisational-group | Duke Global Health Institute | |
pubs.organisational-group | University Institutes and Centers | |
pubs.organisational-group | Institutes and Provost's Academic Units | |
pubs.organisational-group | Pathology | |
pubs.organisational-group | Medicine, Infectious Diseases | |
pubs.organisational-group | Duke Cancer Institute | |
pubs.organisational-group | Institutes and Centers | |
pubs.organisational-group | Surgery, Cardiovascular and Thoracic Surgery | |
pubs.organisational-group | Surgery | |
pubs.organisational-group | Molecular Genetics and Microbiology | |
pubs.organisational-group | Basic Science Departments | |
pubs.publication-status | Published | |
pubs.volume | 18 |
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