Epithelial-mesenchymal transitions and hepatocarcinogenesis.

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Date

2010-04

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Abstract

Epithelial-mesenchymal transitions (EMTs) are believed to play a role in invasion and metastasis of many types of tumors. In this issue of the JCI, Chen et al. show that a gene that has been associated with aggressive biology in hepatocellular carcinomas initiates a molecular cascade that results in EMT.

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Subjects

Animals, Carcinoma, Hepatocellular, Cell Differentiation, DNA Helicases, DNA-Binding Proteins, Epithelial Cells, Humans, Liver Cirrhosis, Liver Neoplasms, Mesoderm, Mice, cdc42 GTP-Binding Protein

Citation

Published Version (Please cite this version)

10.1172/JCI42615

Publication Info

Jou, Janice, and Anna Mae Diehl (2010). Epithelial-mesenchymal transitions and hepatocarcinogenesis. J Clin Invest, 120(4). pp. 1031–1034. 10.1172/JCI42615 Retrieved from https://hdl.handle.net/10161/4329.

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