Electrosprayed core-shell microspheres for protein delivery.

dc.contributor.author

Wu, Yiquan

dc.contributor.author

Liao, I-Chien

dc.contributor.author

Kennedy, Scott J

dc.contributor.author

Du, Jinzhi

dc.contributor.author

Wang, Jun

dc.contributor.author

Leong, Kam W

dc.contributor.author

Clark, Robert L

dc.coverage.spatial

England

dc.date.accessioned

2011-06-21T17:27:17Z

dc.date.issued

2010-07-14

dc.description.abstract

This communication describes a single-step electrospraying technique that generates core-shell microspheres (CSMs) with encapsulated protein as the core and an amphiphilic biodegradable polymer as the shell. The protein release profiles of the electrosprayed CSMs showed steady release kinetics over 3 weeks without a significant initial burst.

dc.description.version

Version of Record

dc.identifier

http://www.ncbi.nlm.nih.gov/pubmed/20485844

dc.identifier.eissn

1364-548X

dc.identifier.uri

https://hdl.handle.net/10161/4129

dc.language

eng

dc.language.iso

en_US

dc.publisher

Royal Society of Chemistry (RSC)

dc.relation.ispartof

Chem Commun (Camb)

dc.relation.isversionof

10.1039/c0cc00535e

dc.relation.journal

Chemical Communications

dc.subject

Kinetics

dc.subject

Microspheres

dc.subject

Polyesters

dc.subject

Polymers

dc.subject

Proteins

dc.title

Electrosprayed core-shell microspheres for protein delivery.

dc.title.alternative
dc.type

Journal article

duke.date.pubdate

2010-00-00

duke.description.issue

26

duke.description.volume

46

pubs.author-url

http://www.ncbi.nlm.nih.gov/pubmed/20485844

pubs.begin-page

4743

pubs.end-page

4745

pubs.issue

26

pubs.organisational-group

Biomedical Engineering

pubs.organisational-group

Duke

pubs.organisational-group

Pratt School of Engineering

pubs.publication-status

Published

pubs.volume

46

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