Blood Lead Levels Among Pregnant Women: Historical Versus Contemporaneous Exposures

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2012-11-01

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Abstract

Blood lead among pregnant women, even at modest levels, may impair offspring cognitive development. We examine whether blood lead levels (BLLs) result from current versus historic exposures, among a cohort of pregnant women. Cumulative logit models were used to characterize the relationship between maternal risk factors and higher BLLs. Maternal blood lead levels more likely result from lead remobilization from historic versus contemporaneous exposures. Even if all lead sources were abated immediately, women and their fetuses would experience lead exposure for decades. This work emphasizes the importance of addressing sources of environmental lead exposure in the United States and internationally.

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blood lead, pregnancy, birth outcomes, lead exposure

Citation

Miranda, M.L.; Edwards, S.E.; Swamy, G.K.; Paul, C.J.; Neelon, B. Blood Lead Levels Among Pregnant Women: Historical Versus Contemporaneous Exposures. Int. J. Environ. Res. Public Health 2010, 7, 1508-1519.

Published Version (Please cite this version)

10.3390/ijerph7041508

Publication Info

Edwards, Sharon E, Marie Lynn Miranda, Brian Hugh Neelon, Christopher J Paul and Geeta Krishna Swamy (2012). Blood Lead Levels Among Pregnant Women: Historical Versus Contemporaneous Exposures. 10.3390/ijerph7041508 Retrieved from https://hdl.handle.net/10161/5976.

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Scholars@Duke

Swamy

Geeta Krishna Swamy

Haywood Brown, MD Distinguished Professor of Women's Health

Geeta Swamy, MD, Haywood Brown, MD Distinguished Professor of Women’s Health, serves as Executive Vice Dean for Clinical Sciences & Research Administration for the Duke University School of Medicine and Associate Vice President for Research for Duke University. In these roles, Dr. Swamy oversees central operations aligned with clinical departments and research centers, facilitating research priorities in collaboration with clinical chairs and vice chairs, and managing research administration and compliance. She works closely with leadership across the Duke Health Integrated Practice (DHIP) and Duke University Health System (DUHS) on areas that intersect with the academic missions. She collaborates with leaders across the Duke University campus to provide a consistent vision for research administration, operations, quality, and accountability. Her responsibilities include overseeing pre- and post-award management for sponsored grants and contracts, human research, research quality, compliance, and integrity, conflict of interest, and other regulatory areas. As a highly accomplished clinician-scientist, Dr. Swamy’s research specializes in perinatal infection, maternal immunization, and complications of pregnancy.


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