The effects of anemia on pregnancy outcome in patients with pyelonephritis.
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OBJECTIVE: Pyelonephritis is a common infectious morbidity of pregnancy. Though anemia is commonly associated with pyelonephritis, there are little data describing the effect of pyelonephritis with anemia on pregnancy outcomes. The purpose of this study was to further assess the association of anemia with infectious morbidity and pregnancy complications among women with pyelonephritis. STUDY DESIGN: We conducted a retrospective cohort study of pregnant women admitted to Duke University Hospital between July 2006 and May 2012 with pyelonephritis. Demographic, laboratory, and clinical data from the subject's pregnancy and hospitalizations were analyzed. Patients with pyelonephritis and anemia (a hematocrit < 32) were compared to those without anemia. Descriptive statistics were used to compare the two groups. RESULTS: 114 pregnant women were admitted with pyelonephritis and 45 (39.5%) had anemia on admission. There was no significant difference in age, race, preexisting medical conditions, or urine bacterial species between patients with anemia and those without. Women with anemia were more likely to deliver preterm (OR 3.3 (95% CI 1.07, 11.4), P = 0.04). When controlling for race and history of preterm delivery, women with anemia continued to have increased odds of preterm birth (OR 6.0, CI 1.4, 35, P = 0.012). CONCLUSION: Women with pyelonephritis and anemia are at increased risk for preterm delivery.
Pregnancy Complications, Infectious
Published Version (Please cite this version)10.1155/2013/780960
Publication InfoDotters-Katz, Sarah K; Grotegut, Chad A; & Heine, R Phillips (2013). The effects of anemia on pregnancy outcome in patients with pyelonephritis. Infect Dis Obstet Gynecol, 2013. pp. 780960. 10.1155/2013/780960. Retrieved from https://hdl.handle.net/10161/11094.
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Assistant Professor of Obstetrics and Gynecology
My passion is for medical education. As a resident, I was recognized for excellence in teaching by the medical students during all four years of my training, and completed the “Resident as Teacher” program during that time as well. I have obtained my Masters of Medical Health Professions Education from Eastern Virginia Medical School from 2016-2017. During that time, I also completed the University of North Carolina Faculty Scholars program and was inducted into the University of
Associate Professor of Obstetrics and Gynecology
I am a specialist in maternal-fetal medicine, which is a subspecialty of OB/GYN that focuses on the care of women with high-risk pregnancies. I serve as the Medical Director of the Labor and Delivery Unit at Duke University Hospital. In that role, and together with our outstanding unit team members, we have the opportunity to help women and their families ensure that they have the safest and best labor and delivery experience possible. My specific clinical int
Professor of Obstetrics and Gynecology
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Dotters-Katz, Sarah K; Patel, Emily; Grotegut, Chad A; Heine, R Phillips (Infect Dis Obstet Gynecol, 2015)OBJECTIVES: Physiologic and immunologic changes in pregnancy result in increased susceptibility to infection. These shifts are more pronounced in pregnancies complicated by multiple gestation. The objective of this study ...
Bates, Shannon M; Middeldorp, Saskia; Rodger, Marc; James, Andra H; Greer, Ian (J Thromb Thrombolysis, 2016-01)Venous thromboembolism (VTE), which may manifest as pulmonary embolism (PE) or deep vein thrombosis (DVT), is a serious and potentially fatal condition. Treatment and prevention of obstetric-related VTE is complicated by ...
Grotegut, Chad A; Chisholm, Christian A; Johnson, Lauren NC; Brown, Haywood L; Heine, R Phillips; James, Andra H (PLoS One, 2014)OBJECTIVE: The number of women aged 45 and older who become pregnant is increasing. The objective of this study was to estimate the risk of medical and obstetric complications among women aged 45 and older. METHODS: The ...