Epidemiology of hypertension in Northern Tanzania: a community-based mixed-methods study.
Abstract
INTRODUCTION: Sub-Saharan Africa is particularly vulnerable to the growing global
burden of hypertension, but epidemiological studies are limited and barriers to optimal
management are poorly understood. Therefore, we undertook a community-based mixed-methods
study in Tanzania to investigate the epidemiology of hypertension and barriers to
care. METHODS: In Northern Tanzania, between December 2013 and June 2015, we conducted
a mixed-methods study, including a cross-sectional household epidemiological survey
and qualitative sessions of focus groups and in-depth interviews. For the survey,
we assessed for hypertension, defined as a single blood pressure ≥160/100 mm Hg, a
two-time average of ≥140/90 mm Hg or current use of antihypertensive medications.
To investigate relationships with potential risk factors, we used adjusted generalised
linear models. Uncontrolled hypertension was defined as a two-time average measurement
of ≥160/100 mm Hg irrespective of treatment status. Hypertension awareness was defined
as a self-reported disease history in a participant with confirmed hypertension. To
explore barriers to care, we identified emerging themes using an inductive approach
within the framework method. RESULTS: We enrolled 481 adults (median age 45 years)
from 346 households, including 123 men (25.6%) and 358 women (74.4%). Overall, the
prevalence of hypertension was 28.0% (95% CI 19.4% to 38.7%), which was independently
associated with age >60 years (prevalence risk ratio (PRR) 4.68; 95% CI 2.25 to 9.74)
and alcohol use (PRR 1.72; 95% CI 1.15 to 2.58). Traditional medicine use was inversely
associated with hypertension (PRR 0.37; 95% CI 0.26 to 0.54). Nearly half (48.3%)
of the participants were aware of their disease, but almost all (95.3%) had uncontrolled
hypertension. In the qualitative sessions, we identified barriers to optimal care,
including poor point-of-care communication, poor understanding of hypertension and
structural barriers such as long wait times and undertrained providers. CONCLUSIONS:
In Northern Tanzania, the burden of hypertensive disease is substantial, and optimal
hypertension control is rare. Transdisciplinary strategies sensitive to local practices
should be explored to facilitate early diagnosis and sustained care delivery.
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https://hdl.handle.net/10161/15851Published Version (Please cite this version)
10.1136/bmjopen-2017-018829Publication Info
Galson, Sophie W; Staton, Catherine A; Karia, Francis; Kilonzo, Kajiru; Lunyera, Joseph;
Patel, Uptal D; ... Stanifer, John W (2017). Epidemiology of hypertension in Northern Tanzania: a community-based mixed-methods
study. BMJ Open, 7(11). pp. e018829. 10.1136/bmjopen-2017-018829. Retrieved from https://hdl.handle.net/10161/15851.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Sophie Wolfe Galson
Assistant Professor of Emergency Medicine
Dr. Galson graduated from Mount Sinai School of Medicine and completed her residency
in Emergency Medicine at the University of Arizona. She has always had a love for
global health and has worked in India, Madagascar and Tanzania during her medical
training. She completed the Global Health Emergency Medicine Fellowship in 2018. Dr.
Galson's research is focused on non-communicable diseases in the emergency department
and linkage to care in Moshi, Tanzania. She
Julian T Hertz
Associate Professor of Emergency Medicine
Julian Hertz, MD, MSc, is an Associate Professor of Emergency Medicine & Global Health.
He graduated summa cum laude from Princeton University and attended medical school
at Duke University, where he received the Dean's Merit Scholarship and the Thomas
Jefferson Award for leadership. He completed his residency training in emergency medicine
at Vanderbilt University Medical Center and his fellowship in Global Health at Duke.Dr.
Hertz's primary interests include globa
Joseph Lunyera
Medical Instructor in the Department of Medicine
I am a clinical epidemiologist with a life-long desire to advance our understanding
of etiologic mechanisms of kidney disease, and to advocate for policies that promote
the highest quality care for individuals with kidney disease. Specifically, I am interested
in delineating mechanisms by which exposures in the social environment perpetuate
disparate adverse kidney outcomes such as chronic kidney disease and acute kidney
injury.
Uptal Dinesh Patel
Adjunct Professor in the Department of Medicine
Uptal Patel, MD is an Adjunct Professor interested in population health with a broad
range of clinical and research experience. As an adult and pediatric nephrologist
with training in health services and epidemiology, his work seeks to improve population
health for patients with kidney diseases through improvements in prevention, diagnosis
and treatment. Prior efforts focused on four inter-related areas that are essential
to improving kidney health: i) reducing the progressi
John W. Stanifer
Adjunct Assistant Professor of Medicine
John W. Stanifer, MD, MSc-GH, is a nephrologist and clinical researcher with a focus
on using translational and trans-disciplinary methods to uncover mechanisms of global health
disparities in kidney disease. John completed his residency training in internal medicine
and global health at Duke, completing the Master of Science in Global Health program
in 2014. He also completed his sub-specialty training in nephrology at Duke, and during
that time, he also completed a fellowship in c
Catherine Ann Staton
Associate Professor of Emergency Medicine
Catherine Staton MD MSc
Dr. Staton is an Associate Professor in Emergency Medicine (EM), Neurosurgery & Global
Health with tenure at Duke University. She is the Director of the GEMINI (Global EM
Innovation & Implementation) Research Center and the EM Vice Chair of Research Strategy
& Faculty Development. Her research integrates innovative implementation methods into
health systems globally to improve access to acute care. In 2012, with an injury registry
at Kilimanjaro Chr
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