Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis

Date
2019-12
Authors
Han, Tao
Jiang, Shulong
Zheng, Hong
Yin, Qing
Xie, Mengyu
Little, Margaret R
Yin, Xiu
Chen, Ming
Song, Su Jung
Beg, Amer A
Pandolfi, Pier Paolo
Wan, Lixin
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Journal article
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https://hdl.handle.net/10161/19230
Published Version (Please cite this version)
10.1038/s41467-019-11618-7
Publication Info
Han, Tao; Jiang, Shulong; Zheng, Hong; Yin, Qing; Xie, Mengyu; Little, Margaret R; ... Wan, Lixin (2019). Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis. Nature Communications, 10(1). 10.1038/s41467-019-11618-7. Retrieved from https://hdl.handle.net/10161/19230.
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Scholars@Duke

Chen

Ming Chen

Associate Professor in Pathology
Our laboratory is interested in understanding the molecular and genetic events underlying cancer progression and metastasis. The focus of our work is a series of genetically engineered mouse models that faithfully recapitulate human disease. Using a combination of mouse genetics, omics technologies, cross-species analyses and in vitro approaches, we aim to identify cancer cell–intrinsic and –extrinsic mechanisms driving metastatic cancer progression, with a long
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