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Psychiatric disorders in inhalant users: results from The National Epidemiologic Survey on Alcohol and Related Conditions.
Abstract
To examine the prevalence and correlates of mood, anxiety, and personality disorders
among lifetime inhalant users.Statistical analyses were based on data from the 2001-2002
National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), a nationally
representative survey of adults in the United States.Inhalant users (N=664) had high
lifetime prevalences of DSM-IV mood (48%), anxiety (36%), and personality (45%) disorders.
Of all inhalant users, 70% met criteria for at least one lifetime mood, anxiety, or
personality disorder and 38% experienced a mood or anxiety disorder in the past year.
Prevalences of comorbid psychiatric disorders varied by gender. Compared with male
inhalant users, female inhalant users had higher prevalences of lifetime dysthymia
(24% versus 16%), any anxiety disorder (53% versus 30%), panic disorder without agoraphobia
(25% versus 11%), and specific phobia (28% versus 14%), but a lower prevalence of
antisocial personality disorder (22% versus 36%). Female inhalant users also were
more likely than male inhalant users to meet criteria for three or more mood or anxiety
disorders (15% versus 8%) in the past year. Among inhalant users with comorbid disorders,
those who developed social or specific phobia typically experienced onset of these
disorders prior to initiation of inhalant use; all other mood and anxiety disorders
usually developed following the onset of inhalant use. Inhalant users who were women,
poor, less educated, with early onset of inhalant use, family histories of psychopathology,
and personal histories of substance abuse treatment had increased odds of psychiatric
disorders.Psychiatric disorders are highly prevalent among inhalant users nationally
and female inhalant users are more likely than male inhalant users to experience multiple
psychiatric disorders. Inhalant use and its consequences among females warrant greater
research attention.
Type
Journal articleSubject
HumansSubstance-Related Disorders
Alcoholism
Administration, Inhalation
Health Surveys
Anxiety Disorders
Mood Disorders
Personality Disorders
Psychotic Disorders
Inhalation
Adult
Aged
Aged, 80 and over
Middle Aged
Income
United States
Female
Male
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https://hdl.handle.net/10161/20017Published Version (Please cite this version)
10.1016/j.drugalcdep.2006.10.012Publication Info
Wu, Li-Tzy; & Howard, Matthew Owen (2007). Psychiatric disorders in inhalant users: results from The National Epidemiologic Survey
on Alcohol and Related Conditions. Drug and alcohol dependence, 88(2-3). pp. 146-155. 10.1016/j.drugalcdep.2006.10.012. Retrieved from https://hdl.handle.net/10161/20017.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Li-Tzy Wu
Professor in Psychiatry and Behavioral Sciences
Education/Training: Pre- and post-doctoral training in mental health service research,
psychiatric epidemiology (NIMH T32), and addiction epidemiology (NIDA T32) from Johns
Hopkins University School of Public Health (Maryland); Fellow of the NIH Summer Institute
on the Design and Conduct of Randomized Clinical Trials.Director: Duke Community Based
Substance Use Disorder Research Program.Research interests: COVID-19, Opioid misuse,
Opioid overdose, Opioid use disorder

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