Recent and active problematic substance use among primary care patients: Results from the alcohol, smoking, and substance involvement screening test in a multisite study.
Abstract
Background: Primary care settings provide salient opportunities for identifying patients with
problematic substance use and addressing unmet treatment need. The aim of this study
was to examine the extent and correlates of problematic substance use by substance-specific
risk categories among primary care patients to inform screening/intervention efforts.
Methods: Data were analyzed from 2000 adult primary care patients aged ≥18 years (56% female)
across 5 clinics in the eastern U.S. Participants completed the Alcohol, Smoking and
Substance Involvement Screening Test (ASSIST). Prevalence and ASSIST-defined risk-level
of tobacco use, alcohol use, and nonmedical/illicit drug use was examined. Multinomial
logistic regression models analyzed the demographic correlates of substance use risk-levels.
Results: Among the total sample, the prevalence of any past 3-month use was 53.9% for alcohol,
42.0% for tobacco, 24.2% for any illicit/Rx drug, and 5.3% for opioids; the prevalence
of ASSIST-defined moderate/high-risk use was 45.1% for tobacco, 29.0% for any illicit/Rx
drug, 14.2% for alcohol, and 9.1% for opioids. Differences in the extent and risk-levels
of substance use by sex, race/ethnicity, and age group were observed. Adjusted logistic
regression showed that male sex, white race, not being married, and having less education
were associated with increased odds of moderate/high-risk use scores for each substance
category; older ages (versus ages 18-25 years) were associated with increased odds
of moderate/high-risk opioid use. Conclusions: Intervention need for problematic substance use was prevalent in this sample. Providers
should maintain awareness and screen for problematic substance use more consistently
in identified high risk populations.
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https://hdl.handle.net/10161/22725Published Version (Please cite this version)
10.1080/08897077.2021.1901176Publication Info
John, William S; Zhu, He; Greenblatt, Lawrence H; & Wu, Li-Tzy (2021). Recent and active problematic substance use among primary care patients: Results from
the alcohol, smoking, and substance involvement screening test in a multisite study.
Substance abuse. pp. 1-6. 10.1080/08897077.2021.1901176. Retrieved from https://hdl.handle.net/10161/22725.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Lawrence Howard Greenblatt
Professor of Medicine
Dr. Greenblatt focuses his professional efforts in 3 domains. First, he provides
care to a busy general internal medicine panel utilizing an approach that is both
patient-centered and evidence-based. Second, he is an active educator routinely providing
clinical teaching to students and residents. He routinely regularly provides faculty
development in teaching and other skills for medical educators across many professions
both in Durham and in the Academic Medicine Education In
William S John
Assistant Professor in Psychiatry and Behavioral Sciences
This author no longer has a Scholars@Duke profile, so the information shown here reflects
their Duke status at the time this item was deposited.
Li-Tzy Wu
Professor in Psychiatry and Behavioral Sciences
Education/Training: Pre- and post-doctoral training in mental health service research,
psychiatric epidemiology (NIMH T32), and addiction epidemiology (NIDA T32) from Johns
Hopkins University School of Public Health (Maryland); Fellow of the NIH Summer Institute
on the Design and Conduct of Randomized Clinical Trials.Director: Duke Community Based
Substance Use Disorder Research Program.Research interests: COVID-19, Opioid misuse,
Opioid overdose, Opioid use disorder
Alphabetical list of authors with Scholars@Duke profiles.

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