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Potentially functional variants of PLCE1 identified by GWASs contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population. 

Wang, Mengyun; Zhang, Ruoxin; He, Jing; Qiu, Lixin; Li, Jin; Wang, Yanong; Sun, Menghong; ... (15 authors) (PloS one, 2012-01)
BACKGROUND: Recent genome-wide association studies (GWAS) have found a single nucleotide polymorphism (SNP, rs2274223 A>G) in PLCE1 to be associated with risk of gastric adenocarcinoma. In the present study, we validated ...
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Pri-miR-124 rs531564 and pri-miR-34b/c rs4938723 polymorphisms are associated with decreased risk of esophageal squamous cell carcinoma in Chinese populations. 

Zhang, Junjie; Huang, Xuewen; Xiao, Juanjuan; Yang, Yajun; Zhou, Yinghui; Wang, Xiaofeng; Liu, Qingmei; ... (18 authors) (PloS one, 2014-01)
MicroRNAs are a new class of small non-protein-coding RNAs that sometimes function as tumor suppressors or oncogenes. Aberrant expression and structural alteration of microRNAs have been reported to be involved in tumorigenesis ...

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Jin, Li (2)
Li, Jin (2)
Qiu, Lixin (2)Wang, Jiucun (2)Wang, Mengyun (2)
Wei, Qingyi (2)
Yang, Jingmin (2)Yang, Yajun (2)He, Jing (1)Huang, Xuewen (1)... View MoreDate Issued2012 (1)2014 (1)TypeJournal article (2)SubjectAdult (2)Aged (2)Asian Continental Ancestry Group (2)Case-Control Studies (2)China (2)Female (2)Genetic Predisposition to Disease (2)
Humans (2)
Male (2)
Middle Aged (2)
... View MoreAffiliation of Duke Author(s)Basic Science Departments (2)Clinical Science Departments (2)
Duke (2)
Duke Cancer Institute (2)Institutes and Centers (2)Medicine (2)Medicine, Medical Oncology (2)Population Health Sciences (2)
School of Medicine (2)
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