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Provider specialty and atrial fibrillation treatment strategies in United States community practice: findings from the ORBIT-AF registry.
(J Am Heart Assoc, 2013-07-18)
BACKGROUND: The prevalence of atrial fibrillation (AF) continues to increase; however,
there are limited data describing the division of care among practitioners in the
community and whether care differs depending on provider ...
Delays in appropriate antibiotic therapy for gram-negative bloodstream infections: a multicenter, community hospital study.
(PLoS One, 2013)
BACKGROUND: Gram-negative bacterial bloodstream infection (BSI) is a serious condition
with estimated 30% mortality. Clinical outcomes for patients with severe infections
improve when antibiotics are appropriately chosen ...
Genome-wide linkage analysis of cardiovascular disease biomarkers in a large, multigenerational family.
(PLoS One, 2013)
Given the importance of cardiovascular disease (CVD) to public health and the demonstrated
heritability of both disease status and its related risk factors, identifying the
genetic variation underlying these susceptibilities ...
Hazard-rate analysis and patterns of recurrence in early stage melanoma: moving towards a rationally designed surveillance strategy.
(PLoS One, 2013)
BACKGROUND: While curable at early stages, few treatment options exist for advanced
melanoma. Currently, no consensus exists regarding the optimal surveillance strategy
for patients after resection. The objectives of this ...
Early adoption of dabigatran and its dosing in US patients with atrial fibrillation: results from the outcomes registry for better informed treatment of atrial fibrillation.
(J Am Heart Assoc, 2013-11-25)
BACKGROUND: Dabigatran is a novel oral anticoagulant approved for thromboprophylaxis
in atrial fibrillation. Adoption patterns of this new agent in community practice
are unknown. METHODS AND RESULTS: We studied patterns ...
Racial differences in the prevalence and outcomes of atrial fibrillation among patients hospitalized with heart failure.
(J Am Heart Assoc, 2013-09-26)
BACKGROUND: The intersection of heart failure (HF) and atrial fibrillation (AF) is
common, but the burden of AF among black patients with HF is poorly characterized.
We sought to determine the prevalence of AF, characteristics, ...
Prolonged B-cell depletion in MuSK myasthenia gravis following rituximab treatment.
(Muscle Nerve, 2013-12)
Assessing acute systemic effects of an inhaled drug with serial echocardiography: a placebo-controlled comparison of inhaled and intravenous dihydroergotamine.
(Drug Des Devel Ther, 2013)
OBJECTIVE: MAP0004 is an investigational product which delivers dihydroergotamine
(DHE) through the lung via a breath-synchronized metered dose inhaler. The objective
of this study was to compare the acute effects of orally ...
Comparison of performance achievement award recognition with primary stroke center certification for acute ischemic stroke care.
(J Am Heart Assoc, 2013-10-14)
BACKGROUND: Hospital certification and recognition programs represent 2 independent
but commonly used systems to distinguish hospitals, yet they have not been directly
compared. This study assessed acute ischemic stroke ...
Alglucosidase alfa enzyme replacement therapy as a therapeutic approach for glycogen storage disease type III.
(Mol Genet Metab, 2013-02)
We investigated the feasibility of using recombinant human acid-α glucosidase (rhGAA,
Alglucosidase alfa), an FDA approved therapy for Pompe disease, as a treatment approach
for glycogen storage disease type III (GSD III). ...