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Now showing items 1-10 of 26
Recovery and survival from aging-associated diseases.
(Exp Gerontol, 2013-08)
OBJECTIVES: Considering disease incidence to be a main contributor to healthy lifespan
of the US elderly population may lead to erroneous conclusions when recovery/long-term
remission factors are underestimated. Using two ...
Transitional probability-based model for HPV clearance in HIV-1-positive adolescent females.
(PLoS One, 2012)
BACKGROUND: HIV-1-positive patients clear the human papillomavirus (HPV) infection
less frequently than HIV-1-negative. Datasets for estimating HPV clearance probability
often have irregular measurements of HPV status and ...
Does surgery improve outcomes for esophageal squamous cell carcinoma? An analysis using the surveillance epidemiology and end results registry from 1998 to 2008.
(J Am Coll Surg, 2012-11)
BACKGROUND: We examined survival associated with locally advanced esophageal squamous
cell cancer (SCC) to evaluate if treatment without surgery could be considered adequate.
STUDY DESIGN: Patients in the Surveillance, ...
Variability in the treatment of elderly patients with stage IIIA (N2) non-small-cell lung cancer.
(J Thorac Oncol, 2013-06)
INTRODUCTION: : We evaluated treatment patterns of elderly patients with stage IIIA
(N2) non-small-cell lung cancer (NSCLC). METHODS: : The use of surgery, chemotherapy,
and radiation for patients with stage IIIA (T1-T3N2M0) ...
Evaluation of genotype-specific survival using joint analysis of genetic and non-genetic subsamples of longitudinal data.
(Biogerontology, 2011-04)
Small sample size of genetic data is often a limiting factor for desirable accuracy
of estimated genetic effects on age-specific risks and survival. Longitudinal non-genetic
data containing information on survival or disease ...
Exploring the association between melanoma and glioma risks.
(Ann Epidemiol, 2014-06)
PURPOSE: Gliomas are one of the most fatal malignancies, with largely unknown etiology.
This study examines a possible connection between glioma and melanoma, which might
provide insight into gliomas' etiology. METHODS: ...
Preoperative CYP2D6 metabolism-dependent β-blocker use and mortality after coronary artery bypass grafting surgery.
(J Thorac Cardiovasc Surg, 2014-04)
OBJECTIVE: Recently, the role of β-blockers (BBs) in reducing perioperative mortality
has been challenged. The conflicting results might have resulted from the extent of
BB metabolism by the cytochrome P-450 (CYP2D6) isoenzyme. ...
Early hematopoiesis inhibition under chronic radiation exposure in humans.
(Radiat Environ Biophys, 2010-05)
The major goal of this study was to identify and quantitatively describe the association
between the characteristics of chronic (low-dose rate) exposure to (low LET) ionizing
radiation and cellularity of peripheral blood ...
Breast cancer as heterogeneous disease: contributing factors and carcinogenesis mechanisms.
(Breast Cancer Res Treat, 2011-07)
The observed bimodal patterns of breast cancer incidence in the U.S. suggested that
breast cancer may be viewed as more than one biological entity. We studied the factors
potentially contributing to this phenomenon, specifically ...
Benefit of adjuvant chemotherapy after resection of stage II (T1-2N1M0) non-small cell lung cancer in elderly patients.
(Ann Surg Oncol, 2015-02)
BACKGROUND: We evaluated the use and efficacy of adjuvant chemotherapy after resection
of T1-2N1M0 non-small cell lung cancer (NSCLC) in elderly patients. METHODS: Factors
associated with the use of adjuvant chemotherapy ...