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Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk.
(Proceedings of the National Academy of Sciences of the United States of America, 2013-11)
Achieving an AIDS-free generation will require elimination of postnatal transmission
of HIV-1 while maintaining the nutritional and immunologic benefits of breastfeeding
for infants in developing regions. Maternal/infant ...
The miR-184 binding-site rs8126 T>C polymorphism in TNFAIP2 is associated with risk of gastric cancer.
(PloS one, 2013-01)
TNFAIP2 is a crucial gene involved in apoptosis. Single nucleotide polymorphisms (SNPs)
in its miRNA binding sites could modulate functions of the miRNA-target genes and
thus risk of cancers. In this study, we investigated ...
Recovery and survival from aging-associated diseases.
(Exp Gerontol, 2013-08)
OBJECTIVES: Considering disease incidence to be a main contributor to healthy lifespan
of the US elderly population may lead to erroneous conclusions when recovery/long-term
remission factors are underestimated. Using two ...
Epidermal growth factor regulates hematopoietic regeneration after radiation injury.
(Nat Med, 2013-03)
The mechanisms that regulate hematopoietic stem cell (HSC) regeneration after myelosuppressive
injury are not well understood. We identified epidermal growth factor (EGF) to be
highly enriched in the bone marrow serum of ...
Variability in the treatment of elderly patients with stage IIIA (N2) non-small-cell lung cancer.
(J Thorac Oncol, 2013-06)
INTRODUCTION: : We evaluated treatment patterns of elderly patients with stage IIIA
(N2) non-small-cell lung cancer (NSCLC). METHODS: : The use of surgery, chemotherapy,
and radiation for patients with stage IIIA (T1-T3N2M0) ...
Providing premedical students with quality clinical and research experience: the Tobacco Science Scholars Program.
(WMJ, 2013-10)
Undergraduate premedical students face a formidable decision as they work to determine
whether to pursue a profession in medicine. Exposure to clinical medicine and research
is essential to inform students what it might ...
The role of therapeutic alliance in mindfulness interventions: therapeutic alliance in mindfulness training for smokers.
(J Clin Psychol, 2013-09)
OBJECTIVE: Mindfulness-based interventions have enjoyed a marked increase in support
within biomedical and psychological research and practice in the past two decades.
Despite the widespread application of these treatments ...
The effect of the home environment on physical activity and dietary intake in preschool children.
(Int J Obes (Lond), 2013-10)
BACKGROUND: The effects of the home environment on child health behaviors related
to obesity are unclear. PURPOSE: To examine the role of the home physical activity
(PA) and food environment on corresponding outcomes in ...
Promoting community practitioners' use of evidence-based approaches to increase breast cancer screening.
(Public Health Nurs, 2013-07)
Many women do not get mammography screenings at the intervals recommended for early
detection and treatment of breast cancer. The Guide to Community Preventive Services
(Community Guide) recommends a range of evidence-based ...
Sickle erythrocytes target cytotoxics to hypoxic tumor microvessels and potentiate a tumoricidal response.
(PLoS One, 2013)
Resistance of hypoxic solid tumor niches to chemotherapy and radiotherapy remains
a major scientific challenge that calls for conceptually new approaches. Here we exploit
a hitherto unrecognized ability of sickled erythrocytes ...