Search
Now showing items 1-10 of 41
The miR-184 binding-site rs8126 T>C polymorphism in TNFAIP2 is associated with risk of gastric cancer.
(PloS one, 2013-01)
TNFAIP2 is a crucial gene involved in apoptosis. Single nucleotide polymorphisms (SNPs)
in its miRNA binding sites could modulate functions of the miRNA-target genes and
thus risk of cancers. In this study, we investigated ...
Provider specialty and atrial fibrillation treatment strategies in United States community practice: findings from the ORBIT-AF registry.
(J Am Heart Assoc, 2013-07-18)
BACKGROUND: The prevalence of atrial fibrillation (AF) continues to increase; however,
there are limited data describing the division of care among practitioners in the
community and whether care differs depending on provider ...
Genome-wide expression profiles of subchondral bone in osteoarthritis.
(Arthritis Res Ther, 2013)
INTRODUCTION: The aim of this study was to evaluate, for the first time, the differences
in gene expression profiles of normal and osteoarthritic (OA) subchondral bone in
human subjects. METHODS: Following histological assessment ...
The role of therapeutic alliance in mindfulness interventions: therapeutic alliance in mindfulness training for smokers.
(J Clin Psychol, 2013-09)
OBJECTIVE: Mindfulness-based interventions have enjoyed a marked increase in support
within biomedical and psychological research and practice in the past two decades.
Despite the widespread application of these treatments ...
Promoting community practitioners' use of evidence-based approaches to increase breast cancer screening.
(Public Health Nurs, 2013-07)
Many women do not get mammography screenings at the intervals recommended for early
detection and treatment of breast cancer. The Guide to Community Preventive Services
(Community Guide) recommends a range of evidence-based ...
Delays in appropriate antibiotic therapy for gram-negative bloodstream infections: a multicenter, community hospital study.
(PLoS One, 2013)
BACKGROUND: Gram-negative bacterial bloodstream infection (BSI) is a serious condition
with estimated 30% mortality. Clinical outcomes for patients with severe infections
improve when antibiotics are appropriately chosen ...
Genome-wide linkage analysis of cardiovascular disease biomarkers in a large, multigenerational family.
(PLoS One, 2013)
Given the importance of cardiovascular disease (CVD) to public health and the demonstrated
heritability of both disease status and its related risk factors, identifying the
genetic variation underlying these susceptibilities ...
Hazard-rate analysis and patterns of recurrence in early stage melanoma: moving towards a rationally designed surveillance strategy.
(PLoS One, 2013)
BACKGROUND: While curable at early stages, few treatment options exist for advanced
melanoma. Currently, no consensus exists regarding the optimal surveillance strategy
for patients after resection. The objectives of this ...
Relationships amongst osteoarthritis biomarkers, dynamic knee joint load, and exercise: results from a randomized controlled pilot study.
(BMC Musculoskelet Disord, 2013-03-27)
BACKGROUND: Little is known about the relationships of circulating levels of biomarkers
of cartilage degradation with biomechanical outcomes relevant to knee osteoarthritis
(OA) or biomarker changes following non-pharmacological ...
Early adoption of dabigatran and its dosing in US patients with atrial fibrillation: results from the outcomes registry for better informed treatment of atrial fibrillation.
(J Am Heart Assoc, 2013-11-25)
BACKGROUND: Dabigatran is a novel oral anticoagulant approved for thromboprophylaxis
in atrial fibrillation. Adoption patterns of this new agent in community practice
are unknown. METHODS AND RESULTS: We studied patterns ...